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Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors
Recently, a series of selective human carboxylesterase inhibitors have been identified based upon the tanshinones, with biologically active molecules containing a 1,2-dione group as part of a naphthoquinone core. Unfortunately, the synthesis of such compounds is complex. Here we describe a novel met...
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| Udgivet i: | Eur J Med Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5863762/ https://ncbi.nlm.nih.gov/pubmed/29499489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.02.052 |
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