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Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones
Carboxylesterases (CE) are ubiquitous enzymes found in both human and animal tissues and are responsible for the metabolism of xenobiotics. This includes numerous natural products, as well as a many clinically used drugs. Hence the activity of these agents is likely dependent upon the levels and loc...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139784/ https://ncbi.nlm.nih.gov/pubmed/21733699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.06.012 |
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