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Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones

Carboxylesterases (CE) are ubiquitous enzymes found in both human and animal tissues and are responsible for the metabolism of xenobiotics. This includes numerous natural products, as well as a many clinically used drugs. Hence the activity of these agents is likely dependent upon the levels and loc...

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Main Authors: Parkinson, Elizabeth I., Hatfield, M. Jason, Tsurkan, Lyudmila, Hyatt, Janice L., Edwards, Carol C., Hicks, Latorya D., Yan, Bing, Potter, Philip M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139784/
https://ncbi.nlm.nih.gov/pubmed/21733699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.06.012
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