Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors

по Tsurkan, Lyudmila G., Hatfield, M. Jason, Edwards, Carol C., Hyatt, Janice L., Potter, Philip M.
Опубликовано 2012

Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (irinotecan; CPT-11) toxici...

по Hicks, Latorya D., Hyatt, Janice L, Stoddard, Shana, Tsurkan, Lyudmila, Edwards, Carol C., Wadkins, Randy M., Potter, Philip M.
Опубликовано 2009

Modulation of Esterified Drug Metabolism by Tanshinones from Salvia miltiorrhiza (“Danshen”)

по Hatfield, M. Jason, Tsurkan, Lyudmila G., Hyatt, Janice L., Edwards, Carol C., Lemoff, Andrew, Jeffries, Cynthia, Yan, Bing, Potter, Philip M.
Опубликовано 2013

Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11

по Hatfield, M. Jason, Tsurkan, Lyudmila, Garrett, Michael, Shaver, Timothy M., Hyatt, Janice L., Edwards, Carol C., Hicks, Latorya D., Potter, Philip M.
Опубликовано 2010

Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones

по Parkinson, Elizabeth I., Hatfield, M. Jason, Tsurkan, Lyudmila, Hyatt, Janice L., Edwards, Carol C., Hicks, Latorya D., Yan, Bing, Potter, Philip M.
Опубликовано 2011

Carboxylesterases: General detoxifying enzymes

по Hatfield, M. Jason, Umans, Robyn A., Hyatt, Janice L., Edwards, Carol C, Wierdl, Monika, Tsurkan, Lyudmila, Taylor, Michael R., Potter, Philip M.
Опубликовано в: Chem Biol Interact (2016)

Analysis of the Inhibition of Mammalian Carboxylesterases by Novel Fluorobenzoins and Fluorobenzils

по Hicks, Latorya D., Hyatt, Janice L, Moak, Teri, Edwards, Carol C., Tsurkan, Lyudmila, Wierdl, Monika, Ferreira, Antonio, Wadkins, Randy M., Potter, Philip M.
Опубликовано 2007

Structure-Activity Relationships of Substituted 1-Pyridyl-2-Phenyl-1,2-Ethanediones: Potent, Selective Carboxylesterase Inhibitors

по Young, Brandon M., Hyatt, Janice L., Bouck, David C., Chen, Taosheng, Hanumesh, Parimala, Price, Jeanine, Boyd, Vincent A., Potter, Philip M., Webb, Thomas R.
Опубликовано 2010

Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling

по Hatfield, M. Jason, Chen, Jingwen, Fratt, Ellie M., Chi, Liying, Bollinger, John C., Binder, Randall J., Bowling, John, Hyatt, Janice L., Scarborough, Jerrod, Jeffries, Cynthia, Potter, Philip M.
Опубликовано в: J Med Chem (2017)