Resultados da pesquisa - (((mur OR muir) j) OR (((eun a) OR (eun ju)))) med chem

1

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Use of Ionically Tagged Glycosyl Donors in the Synthesis of Oligosaccharide Libraries

Por Kim, Eun Ju, Gray, Gary R.
Publicado em 2009

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2

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Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors

Por Song, Kwang-Seop, Lee, Suk Ho, Kim, Min Ju, Seo, Hee Jeong, Lee, Junwon, Lee, Sung-Han, Jung, Myung Eun, Son, Eun-Jung, Lee, MinWoo, Kim, Jeongmin, Lee, Jinhwa
Publicado em 2010

“... of these compounds have been further evaluated on a urinary glucose excretion test and the urine volumes excreted....”
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3

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OGA inhibition by GlcNAc-selenazoline

Por Kim, Eun Ju, Love, Dona C., Darout, Etzer, Abdo, Mohannad, Rempel, Brian, Withers, Stephen G., Rablen, Paul R., Hanover, John A., Knapp, Spencer
Publicado em 2010

“... only at the chalcogen atom (Se for S), is a much weaker inhibitor in a direct OGA assay. In human cells...”
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4

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Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Por Jo, Hyo Sang, Cha, Hyun Ju, Kim, Sang Jin, Yeo, Hyeon Ji, Cho, Su Bin, Park, Jung Hwan, Lee, Chi Hern, Yeo, Eun Ji, Choi, Yeon Joo, Eum, Won Sik, Choi, Soo Young
Publicado no Med Chem Res (2016)

“... pancreatic β-cell (RINm5F) death using cell permeable wild-type and mutant-type (C106A) Tat-DJ-1 proteins...”
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5

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Structure–Activity Studies of Divin: An Inhibitor of Bacterial Cell Division

Por Zhou, Maoquan, Eun, Ye-Jin, Guzei, Ilia A., Weibel, Douglas B.
Publicado em 2013

“... of divin, a small molecule that blocks bacterial division by perturbing the assembly of proteins...”
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6

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Simultaneous determination of methylcarbamate and ethylcarbamate in fermented foods and beverages by derivatization and GC-MS analysis

Por Shin, Ho-Sang, Yang, Eun-Young
Publicado em 2012

“... in fermented food and beverages. In order to estimate the risk for their exposure, a sensitive simultaneous...”
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7

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Structure Activity Relationships of 1,4-Dihydropyridines That Act as Enhancers of the Vanilloid Receptor 1 (TRPV1)

Por Roh, Eun Joo, Keller, Jason M., Olah, Zoltan, Iadarola, Michael J., Jacobson, Kenneth A.
Publicado em 2008

“...Vanilloid agonists such as capsaicin activate ion flux through the TRPV1 channel, a heat...”
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8

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Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding...

Por Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

“... pentapeptide, PLHSpT (1a) increases affinity. For certain analogues, approximately two orders-of-magnitude...”
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9

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(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5

Por Blasdel, Landy K., Lee, DongEun, Sun, Binyuan, Myers, Andrew G.
Publicado em 2013

“...Analogs of salinsporamide A with variations of the C2 and C5 substituents are prepared in 8–10...”
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10

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Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X(7) receptor

Por Lee, Ga Eun, Joshi, Bhalchandra V., Chen, Wangzhong, Jeong, Lak Shin, Moon, Hyung Ryong, Jacobson, Kenneth A., Kim, Yong-Chul
Publicado em 2007

“..., that is, uptake of a fluorescent dye (ethidium bromide) in stably transfected HEK293 cells and IL-1β release...”
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11

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Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - a novel class of compounds with potent activity against acute myeloid leukemia cells

Por Carter-Cooper, Brandon A., Fletcher, Steven, Ferraris, Dana, Choi, Eun Yong, Kronfli, Dahlia, Dash, Smaraki, Truong, Phuc, Sausville, Edward A., Lapidus, Rena G., Emadi, Ashkan
Publicado no Bioorg Med Chem Lett (2016)

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12

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Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Por Qian, Wenjian, Park, Jung-Eun, Liu, Fa, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

“... been little examination of pThr/pSer mimetics within a PBD context. Our current paper compares...”
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13

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Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

Por Liao, Chenzhong, Park, Jung-Eun, Bang, Jeong K., Nicklaus, Marc C., Lee, Kyung S.
Publicado em 2010

“... pocket via π−π stacking and hydrogen-bonding interactions, thus providing a rationale for designing novel...”
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14

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Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles

Por Kuo, Cheng-Hsiang, Leon, Lorraine, Chung, Eun Ji, Huang, Ru-Ting, Sontag, Timothy J., Reardon, Catherine A., Getz, Godfrey S., Tirrell, Matthew, Fang, Yun
Publicado no J Mater Chem B Mater Biol Med (2014)

“... of their ability to encapsulate charged nucleic acids forming a core by neutralizing their charge, while...”
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15

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Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity Via N5 Substitution

Por Cawrse, Brian M., Lapidus, Rena S., Cooper, Brandon, Choi, Eun Yong, Seley-Radtke, Katherine L.
Publicado no ChemMedChem (2017)

“... to investigate the PK profile of these compounds, a series of halogenated pyrrolo[3,2-d]pyrimidine compounds...”
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16

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Jostling for Position: Optimizing Linker Location in the Design of Estrogen Receptor-targeting PROTACs

Por Cyrus, Kedra, Wehenkel, Marie, Choi, Eun-Young, Lee, Hyosung, Swanson, Hollie, Kim, Kyung-Bo
Publicado em 2010

“.... With this in mind, we previously demonstrated that PROTACs effectively induce degradation of the ER as a proof...”
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17

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Optimizing Thiadiazole Analogues of Resveratrol vs. Three Chemopreventive Targets

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara, Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2011

“.... Replacement of the stilbene ethylenic bridge of resveratrol with a 1,2,4-thiadiazole heterocycle...”
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18

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Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors

Por Zhu, Jin-Yi, Cuellar, Rebecca A., Berndt, Norbert, Lee, Hee Eun, Olesen, Sanne H., Martin, Mathew P., Jensen, Jeffrey T., Georg, Gunda I., Schönbrunn, Ernst
Publicado no J Med Chem (2017)

“... of activation. A series of crystal structures reveal unique features that distinguish Wee1 and Wee2 from Myt1...”
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19

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Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2012

“...NAD(P)H:quinone reductase 1 (QR1) belongs to a class of enzymes called cytoprotective enzymes...”
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20

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Polymer-Protein Hydrogel Nanomatrix for Stabilization of Indocyanine Green towards Targeted Fluorescence and Photoacoustic Bio-imaging

Por Yoon, Hyung Ki, Ray, Aniruddha, Lee, Yong-Eun Koo, Kim, Gwangseong, Wang, Xueding, Kopelman, Raoul
Publicado em 2013

“...Indocyanine green (ICG) is an optical contrast agent commonly used for a variety of imaging...”
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