Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis

Por Jarrad, A.M., Debnath, A., Miyamoto, Y., Hansford, K.A., Pelingon, R., Butler, M.S., Bains, T., Karoli, T., Blaskovich, M.A.T., Eckmann, L., Cooper, M.A.
Publicado no Eur J Med Chem (2016)

Novel c-Met Inhibitory Olive Secoiridoid Semisynthetic Analogs for the Control of Invasive Breast Cancer

Por Mohyeldin, Mohamed M., Busnena, Belnaser A., Akl, Mohamed R., Dragoi, Ana Maria, Cardelli, James A., El Sayed, Khalid A.
Publicado no Eur J Med Chem (2016)

Development of GLUT4-selective antagonists for multiple myeloma therapy

Por Wei, Changyong, Bajpai, Richa, Sharma, Horrick, Heitmeier, Monique, Jain, Atul D., Matulis, Shannon M., Nooka, Ajay K., Mishra, Rama K., Hruz, Paul W., Schiltz, Gary E., Shanmugam, Mala
Publicado no Eur J Med Chem (2017)

Photosensitizer (PS)-Cyanine Dye (CD) Conjugates: Impact of the Linkers Joining the PS and CD Moieties and Their Orientation in Tumor-Uptake and Photodynamic Therapy (PDT)

Por James, Nadine S., Joshi, Penny, Ohulchanskyy, Tymish Y., Chen, Yihui, Tabaczynski, Walter, Durrani, Farukh, Shibata, Masayuki, Pandey, Ravindra K.
Publicado no Eur J Med Chem (2016)

2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition

Por Romagnoli, Romeo, Salvador, Maria Kimatrai, Ortega, Santiago Schiaffino, Baraldi, Pier Giovanni, Oliva, Paola, Baraldi, Stefania, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Mattiuzzo, Elena, Basso, Giuseppe, Viola, Giampietro
Publicado no Eur J Med Chem (2018)

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutan...

Por Tian, Ye, Liu, Zhaoqiang, Liu, Jinghan, Huang, Boshi, Kang, Dongwei, Zhang, Heng, De Clercq, Erik, Daelemans, Dirk, Pannecouque, Christophe, Lee, Kuo-Hsiung, Chen, Chin-Ho, Zhan, Peng, Liu, Xinyong
Publicado no Eur J Med Chem (2018)

Structure-Activity Relationship and Pharmacokinetic Studies of 3-O-Substitutedflavonols as Anti-Prostate Cancer Agents

Por Li, Xiang, Zhang, Changde, Guo, Shanchun, Rajaram, Pravien, Lee, Maizie, Chen, Guanglin, Fong, Ryan, Gonzalez, Aaron, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Eur J Med Chem (2018)

MMB triazole analogues are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells

Por Janganati, Venumadhav, Ponder, Jessica, Balasubramaniam, Meenakshisundaram, Bhat-Nakshatri, Poornima, Bar, Eli E., Nakshatri, Harikrishna, Jordan, Craig T., Crooks, Peter A.
Publicado no Eur J Med Chem (2018)

Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inh...

Por Srinivasan, Bharath, Tonddast-Navaei, Sam, Skolnick, Jeffrey
Publicado no Eur J Med Chem (2015)

Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Por Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Publicado no Eur J Med Chem (2015)

Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors

Por Yu, Xufen, Zhang, Mingming, Annamalai, Arasu, Bansod, Priyanka, Narula, Gagandeep, Tse-Dinh, Yuk-Ching, Sun, Dianqing
Publicado no Eur J Med Chem (2016)

Synthesis and Pharmacological Evaluation of Neurosteroid Photoaffinity Ligands

Por Savechenkov, Pavel Y., Chiara, David C., Desai, Rooma, Stern, Alexander T., Zhou, Xiaojuan, Ziemba, Alexis M., Szabo, Andrea L., Zhang, Yinghui, Cohen, Jonathan B., Forman, Stuart A., Miller, Keith W., Bruzik, Karol S.
Publicado no Eur J Med Chem (2017)

Bimetallic titanocene-gold phosphane complexes inhibit invasion, metastasis, and angiogenesis-associated signaling molecules in renal cancer

Por Elie, Benelita T., Fernández-Gallardo, Jacob, Curado, Natalia, Cornejo, Mike A., Ramos, Joe W., Contel, María
Publicado no Eur J Med Chem (2018)

Safety of outpatient anterior cervical discectomy and fusion: a systematic review and meta-analysis

Por Ban, Dexiang, Liu, Yang, Cao, Taiwei, Feng, Shiqing
Publicado no Eur J Med Res (2016)

Limitations in clinical outcome after posterior stabilization of thoracolumbar fractures do not correlate with dynamic trunk muscle dysfunction: an ultrasound controlled prospectiv...

Por Pishnamaz, Miguel, Schemmann, Ulrike, Herren, Christian, Horst, Klemens, Hildebrand, Frank, Kobbe, Philipp, Pape, Hans-Christoph
Publicado no Eur J Med Res (2018)

The value of [(11)C]-acetate PET and [(18)F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab

Por Li, Shuren, Peck-Radosavljevic, Markus, Ubl, Philipp, Wadsak, Wolfgang, Mitterhauser, Markus, Rainer, Eva, Pinter, Matthias, Wang, Hao, Nanoff, Christian, Kaczirek, Klaus, Haug, Alexander, Hacker, Marcus
Publicado no Eur J Nucl Med Mol Imaging (2017)

Prognostic value of posttreatment (18)F-FDG PET/CT and predictors of metabolic response to therapy in patients with locally advanced cervical cancer treated with concomitant chemor...

Por Lima, Giacomo Maria, Matti, Antonella, Vara, Giulio, Dondi, Giulia, Naselli, Nicoletta, De Crescenzo, Eugenia Maria, Morganti, Alessio Giuseppe, Perrone, Anna Myriam, De Iaco, Pierandrea, Nanni, Cristina, Fanti, Stefano
Publicado no Eur J Nucl Med Mol Imaging (2018)

Synthesis of N3-Substituted Carboranyl Thymidine Bioconjugates and their Evaluation as Substrates of Recombinant Human Thymidine Kinase 1

Por Agarwal, Hitesh K., McElroy, Craig A., Sjuvarsson, Elena, Eriksson, Staffan, Darby, Michael V., Tjarks, Werner
Publicado em 2012

Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico

Por Ortiz-Ortiz, Julio, Alarcón-Romero, Luz del Carmen, Jiménez-López, Marco Antonio, Garzón-Barrientos, Víctor Hugo, Calleja-Macías, Itzel, Barrera-Saldaña, Hugo Alberto, Leyva-Vázquez, Marco Antonio, Illades-Aguiar, Berenice
Publicado no Virol J (2015)

Pentapeptides for the treatment of small cell lung cancer: Optimisation by N(ind)-alkyl modification of the tryptophan side chain

Por Haitham Abusara, Osama, Freeman, Sally, Aojula, Harmesh Singh
Publicado no Eur J Med Chem (2017)