Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer

Por Jiang, Quan, Zheng, Shilong, Wang, Guangdi
Publicado em 2013

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore

Por Du, Lupei, Li, Minyong, Zheng, Shilong, Wang, Binghe
Publicado em 2008

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

Por Mottamal, Madhusoodanan, Zheng, Shilong, Huang, Tien L., Wang, Guangdi
Publicado no Molecules (2015)

Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer

Por Jiang, Quan, Zhong, Qiu, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi
Publicado em 2012

Boronic Prodrug of Endoxifen as an Effective Hormone Therapy for Breast Cancer

Por Zhang, Changde, Zhong, Qiu, Zhang, Qiang, Zheng, Shilong, Miele, Lucio, Wang, Guangdi
Publicado no Breast Cancer Res Treat (2015)

Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

Por Zhong, Qiu, Zhang, Changde, Zhang, Qiang, Miele, Lucio, Zheng, Shilong, Wang, Guangdi
Publicado no BMC Cancer (2015)

Ligands of Therapeutic Utility for the Liver X Receptors

Por Komati, Rajesh, Spadoni, Dominick, Zheng, Shilong, Sridhar, Jayalakshmi, Riley, Kevin E., Wang, Guangdi
Publicado no Molecules (2017)

Design and synthesis of novel hydroxyanthraquinone nitrogen mustard derivatives as potential anticancer agents via a bioisostere approach

Por Zhao, Li-Ming, Ma, Feng-Yan, Jin, Hai-Shan, Zheng, Shilong, Zhong, Qiu, Wang, Guangdi
Publicado no Eur J Med Chem (2015)

A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models

Por Li, Xiang, Chen, Guanglin, Zhang, Xiaojie, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Bioorg Med Chem Lett (2016)

Chemical Validation of Phosphodiesterase C as a Chemotherapeutic Target in Trypanosoma cruzi, the Etiological Agent of Chagas' Disease

Por King-Keller, Sharon, Li, Minyong, Smith, Alyssa, Zheng, Shilong, Kaur, Gurpreet, Yang, Xiaochuan, Wang, Binghe, Docampo, Roberto
Publicado em 2010

Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations

Por Vue, Bao, Zhang, Sheng, Zhang, Xiaojie, Parisis, Konstantinos, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Eur J Med Chem (2015)

Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents

Por Zheng, Shilong, Zhong, Qiu, Mottamal, Madhusoodanan, Zhang, Qiang, Zhang, Changde, LeMelle, Elise, McFerrin, Harris, Wang, Guangdi
Publicado em 2014

Design, Synthesis, and Biological Evaluation of 1,9-Diheteroarylnona-1,3,6,8-tetraen-5-ones as a New Class of Anti-Prostate Cancer Agents

Por Zhang, Xiaojie, Wang, Rubing, Perez, German Ruiz, Chen, Guanglin, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Bioorg Med Chem (2016)

Synthesis and Evaluation of 1,7-Diheteroarylhepta-1,4,6-trien-3-ones as Curcumin-Based Anticancer Agents

Por Wang, Rubing, Zhang, Xiaojie, Chen, Chengsheng, Chen, Guanglin, Zhong, Qiu, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Eur J Med Chem (2016)

Design, Synthesis, and Structure–Activity Relationship, Molecular Modeling, and NMR Studies of a Series of Phenyl Alkyl Ketones as Highly Po...

Por Zheng, Shilong, Kaur, Gurpreet, Wang, Huanchen, Li, Minyong, Macnaughtan, Megan, Yang, Xiaochuan, Reid, Suazette, Prestegard, James, Wang, Binghe, Ke, Hengming
Publicado em 2008

Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

Por Zheng, Shilong, Zhong, Qiu, Jiang, Quan, Mottamal, Madhusoodanan, Zhang, Qiang, Zhu, Naijue, Burow, Matthew E., Worthylake, Rebecca A., Wang, Guangdi
Publicado em 2013

Design, Synthesis, and Evaluation of Genistein Analogues as Anti-Cancer Agents

Por Xiong, Pahoua, Wang, Rubing, Zhang, Xiaojie, Torre, Eduardo DeLa, Leon, Francisco, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Anticancer Agents Med Chem (2015)

Structure–Activity Relationship and Pharmacokinetic Studies of 1,5-Diheteroarylpenta-1,4-dien-3-ones: A Class of Promising Curcumin-Based Anticancer Agents

Por Wang, Rubing, Chen, Chengsheng, Zhang, Xiaojie, Zhang, Changde, Zhong, Qiu, Chen, Guanglin, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no J Med Chem (2015)

3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells

Por Zhang, Sheng, Vue, Bao, Huang, Michael, Zhang, Xiaojie, Lee, Timmy, Chen, Guanglin, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Bioorg Med Chem Lett (2016)

Design, Synthesis, and Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells

Por Strong, Amy L., Jiang, Quan, Zhang, Qiang, Zheng, Shilong, Boue, Stephen M., Elliott, Steven, Burow, Matthew E., Bunnell, Bruce A., Wang, Guangdi
Publicado em 2013