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Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

[Image: see text] Effective inhibitors of cancer cell migration and invasion can potentially lead to clinical applications as a therapy to block tumor metastasis, the primary cause of death in cancer patients. To this end, we have designed and synthesized a series of thiazole derivatives that showed...

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Detalhes bibliográficos
Main Authors: Zheng, Shilong, Zhong, Qiu, Jiang, Quan, Mottamal, Madhusoodanan, Zhang, Qiang, Zhu, Naijue, Burow, Matthew E., Worthylake, Rebecca A., Wang, Guangdi
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601768/
https://ncbi.nlm.nih.gov/pubmed/23526571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300322n
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