Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. The development of drugs that are active against several trypanosomatids...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Med Chem
Prif Awduron: Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Editions Scientifiques Elsevier 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638191/
https://ncbi.nlm.nih.gov/pubmed/26479031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.10.007
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