Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. The development of drugs that are active against several trypanosomatids...

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Опубликовано в: :Eur J Med Chem
Главные авторы: Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Формат: Artigo
Язык:Inglês
Опубликовано: Editions Scientifiques Elsevier 2015
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638191/
https://ncbi.nlm.nih.gov/pubmed/26479031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.10.007
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