Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. The development of drugs that are active against several trypanosomatids...

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Dades bibliogràfiques
Publicat a:Eur J Med Chem
Autors principals: Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Format: Artigo
Idioma:Inglês
Publicat: Editions Scientifiques Elsevier 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638191/
https://ncbi.nlm.nih.gov/pubmed/26479031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.10.007
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