Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

Por Sandee, Duanpen, Morrissey, Kari, Agrawal, Vishal, Tam, Harrison K., Kramer, Melissa A., Tracy, Timothy S., Giacomini, Kathleen M., Miller, Walter L.
Publicado no Pharmacogenet Genomics (2010)

Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in vitro and in vivo nicotine metabolism

Por Tanner, Julie-Anne, Zhu, Andy Z., Claw, Katrina G., Prasad, Bhagwat, Korchina, Viktoriya, Hu, Jianhong, Doddapaneni, HarshaVardhan, Muzny, Donna M., Schuetz, Erin G., Lerman, Caryn, Thummel, Kenneth E., Scherer, Steven E., Tyndale, Rachel F.
Publicado no Pharmacogenet Genomics (2018)

Brain Neurotransmitter Transporter/Receptor Genomics and Efavirenz Central Nervous System Adverse Events

Por Haas, David W., Bradford, Yuki, Verma, Anurag, Verma, Shefali S., Eron, Joseph J., Gulick, Roy M., Riddler, Sharon, Sax, Paul E., Daar, Eric S., Morse, Gene D., Acosta, Edward P., Ritchie, Marylyn D.
Publicado no Pharmacogenet Genomics (2018)

ROLE OF CYTOCHROME P450 2C8 AND 2J2 GENOTYPE IN CALCINEURIN INHIBITOR INDUCED CHRONIC KIDNEY DISEASE

Por Smith, Helen E., Jones, JP., Kalhorn, Thomas F., Farin, Fredrico M., Stapleton, Patricia L., Davis, Connie L., Perkins, James D., Blough, David K., Hebert, Mary F., Thummel, Kenneth E., Totah, Rheem A.
Publicado em 2008

A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background

Por García-Closas, Montserrat, Hein, David W., Silverman, Debra, Malats, Núria, Yeager, Meredith, Jacobs, Kevin, Doll, Mark A, Figueroa, Jonine D, Baris, Dalsu, Schwenn, Molly, Kogevinas, Manolis, Johnson, Alison, Chatterjee, Nilanjan, Moore, Lee E., Moeller, Timothy, Real, Francisco X., Chanock, Stephen, Rothman, Nathaniel
Publicado em 2011

Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics

Por Sun, Dongxiao, Chen, Gang, Dellinger, Ryan W., Sharma, Arun K., Lazarus, Philip
Publicado em 2010

Identification of novel functional Organic Anion-transporting Polypeptide 1B3 (OATP1B3) polymorphisms and assessment of substrate specificity

Por Schwarz, Ute I., Meyer zu Schwabedissen, Henriette E., Tirona, Rommel G., Suzuki, Atsuko, Leake, Brenda F., Mokrab, Younes, Mizuguchi, Kenji, Ho, Richard H., Kim, Richard B.
Publicado em 2011

Glucuronidation of trans-3′-hydroxycotinine by UGT2B17 and UGT2B10

Por Chen, Gang, Giambrone, Nino E., Lazarus, Philip
Publicado em 2012

Gene panels to help identify subgroups at high and low risk of CHD among those randomized to antihypertensive treatment: The GenHAT Study

Por Lynch, Amy I., Eckfeldt, John H., Davis, Barry R., Ford, Charles E., Boerwinkle, Eric, Leiendecker-Foster, Catherine, Arnett, Donna K.
Publicado em 2012

The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal

Por Jungsuwadee, Paiboon, Zhao, Tianyong, Stolarczyk, Elzbieta I., Paumi, Christian M., Butterfield, D. Allan, St.Clair, Daret K., Vore, Mary
Publicado em 2012

Multiple genetic variants predict steady-state nevirapine clearance in HIV-infected Cambodians

Por Bertrand, Julie, Chou, Monidarin, Richardson, Danielle M., Verstuyft, Céline, Leger, Paul D., Mentré, France, Taburet, Anne-Marie, Haas, David W.
Publicado em 2012

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

Por Holzinger, Emily R., Grady, Benjamin, Ritchie, Marylyn D., Ribaudo, Heather J., Acosta, Edward P., Morse, Gene D., Gulick, Roy M., Robbins, Gregory K., Clifford, David B., Daar, Eric S., McLaren, Paul, Haas, David W.
Publicado em 2012

Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS

Por Liptrott, Neill J., Pushpakom, Sudeep, Wyen, Christoph, Fätkenheuer, Gerd, Hoffmann, Christian, Mauss, Stefan, Knechten, Heribert, Brockmeyer, Norbert H., Hopper-Borge, Elizabeth, Siccardi, Marco, Back, David J., Khoo, Saye H., Pirmohamed, Munir, Owen, Andrew
Publicado em 2012

A Pharmacogenetic Candidate Gene Study of Tenofovir-Associated Fanconi Syndrome

Por Dahlin, Amber, Wittwer, Matthias, de la Cruz, Melanie, Woo, Jonathan M., Bam, Rujuta, Scharen-Guivel, Valeska, Flaherty, John, Ray, Adrian S., Cihlar, Tomas, Gupta, Samir K., Giacomini, Kathleen M.
Publicado no Pharmacogenet Genomics (2015)

Evaluation of CYP2D6 enzyme activity using a Dextromethorphan Breath Test in Women Receiving Adjuvant Tamoxifen

Por Safgren, Stephanie L., Suman, Vera J., Kosel, Matthew L., Gilbert, Judith A, Buhrow, Sarah A., Black, John L., Northfelt, Donald W., Modak, Anil S., Rosen, David, Ingle, James N., Ames, Matthew M., Reid, Joel M., Goetz, Matthew P.
Publicado no Pharmacogenet Genomics (2015)

Genome-wide association study of paliperidone efficacy

Por Li, Qingqin, Wineinger, Nathan E., Fu, Dong-Jing, Libiger, Ondrej, Alphs, Larry, Savitz, Adam, Gopal, Srihari, Cohen, Nadine, Schork, Nicholas J.
Publicado no Pharmacogenet Genomics (2017)

Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202

Por Verma, Anurag, Bradford, Yuki, Verma, Shefali S., Pendergrass, Sarah A., Daar, Eric S., Venuto, Charles, Morse, Gene D., Ritchie, Marylyn D., Haas, David W.
Publicado no Pharmacogenet Genomics (2017)

SNP discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene

Por Innocenti, Federico, Liu, Wanqing, Fackenthal, Donna, Ramírez, Jacqueline, Chen, PeiXian, Ye, Xin, Wu, Xiaolin, Zhang, Wei, Mirkov, Snezana, Das, Soma, Cook, Edwin, Ratain, Mark J.
Publicado em 2008

Genetic Variation in Cholesterol Ester Transfer Protein (CETP), Serum CETP Activity, and Coronary Artery Disease (CAD) Risk in Asian Indian Diabetic Cohort

Por Schierer, Ashley, Been, Latonya F., Ralhan, Sarju, Wander, Gurpreet S., Aston, Christopher E., Sanghera, Dharambir K.
Publicado em 2012

Pharmacogenetics in American Indian Populations: Analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes

Por Fohner, Alison, Muzquiz, LeeAnna I., Austin, Melissa A., Gaedigk, Andrea, Gordon, Adam, Thornton, Timothy, Rieder, Mark J., Pershouse, Mark A., Putnam, Elizabeth A., Howlett, Kevin, Beatty, Patrick, Thummel, Kenneth E., Woodahl, Erica L.
Publicado em 2013