Pharmacogenetics in American Indian Populations: Analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes

OBJECTIVES: Cytochrome P450 enzymes play a dominant role in drug elimination and variation in these genes is a major source of interindividual differences in drug response. Little is known, however, about pharmacogenetic variation in American Indian and Alaska Native (AI/AN) populations. We have dev...

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Auteurs principaux: Fohner, Alison, Muzquiz, LeeAnna I., Austin, Melissa A., Gaedigk, Andrea, Gordon, Adam, Thornton, Timothy, Rieder, Mark J., Pershouse, Mark A., Putnam, Elizabeth A., Howlett, Kevin, Beatty, Patrick, Thummel, Kenneth E., Woodahl, Erica L.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937472/
https://ncbi.nlm.nih.gov/pubmed/23778323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283629ce9
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