SNP discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene

OBJECTIVE: UGT2B7 plays a central role in the liver-mediated biotransformation of endogenous and exogenous compounds. The genetic basis of interindividual variability in UGT2B7 function is unknown. This study aimed to discover novel gene variants of functional significance. METHODS: Caucasian human...

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Autores principales: Innocenti, Federico, Liu, Wanqing, Fackenthal, Donna, Ramírez, Jacqueline, Chen, PeiXian, Ye, Xin, Wu, Xiaolin, Zhang, Wei, Mirkov, Snezana, Das, Soma, Cook, Edwin, Ratain, Mark J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680356/
https://ncbi.nlm.nih.gov/pubmed/18622261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283037fe4
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