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Identification of novel functional Organic Anion-transporting Polypeptide 1B3 (OATP1B3) polymorphisms and assessment of substrate specificity
OBJECTIVE: The uptake carrier Organic Anion-transporting Polypeptide 1B3 (OATP1B3, gene SLCO1B3) is involved in the hepatic clearance of xenobiotics including statins, taxanes and mycophenolic acid. We thought to assess the SLCO1B3 coding region for yet unidentified polymorphisms, and to analyze the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044558/ https://ncbi.nlm.nih.gov/pubmed/21278621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328342f5b1 |
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