Contribution of hepatic organic anion transporting polypeptides (OATPs) to docetaxel uptake and clearance

The antimicrotubular agent docetaxel is a widely used chemotherapeutic drug for the treatment of multiple solid tumors and is predominantly dependent on hepatic disposition. In this study, we evaluated drug uptake transporters capable of transporting radiolabeled docetaxel. By screening an array of...

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Bibliografiske detaljer
Udgivet i:	Mol Cancer Ther
Main Authors:	Lee, Hannah H., Leake, Brenda F., Teft, Wendy, Tirona, Rommel G., Kim, Richard B., Ho, Richard H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2015
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4394048/ https://ncbi.nlm.nih.gov/pubmed/25695959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0547
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Contribution of hepatic organic anion transporting polypeptides (OATPs) to docetaxel uptake and clearance

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