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Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance

The organic anion-transporting polypeptides represent an important family of drug uptake transporters that mediate the cellular uptake of a broad range of substrates including numerous drugs. Doxorubicin is a highly efficacious and well-established anthracycline chemotherapeutic agent commonly used...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Lee, Hannah H., Leake, Brenda F., Kim, Richard B., Ho, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198512/
https://ncbi.nlm.nih.gov/pubmed/27777271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.105544
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