Characterization of 22 Antituberculosis Drugs for Inhibitory Interaction Potential on Organic Anionic Transporter Polypeptide (OATP)-Mediated Uptake

We investigated the inhibitory interaction potential of 22 currently marketed antituberculosis (TB) drugs on organic anion-transporting polypeptide 1B1 (OATP1B1)-, OATP2B1-, and OATP1B3-mediated uptake using in vitro Xenopus oocytes and HEK cells. Rifabutin, ethambutol, amoxicillin, linezolid, p-ami...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Parvez, M. Masud, Jung, Jin Ah, Shin, Ho Jung, Kim, Dong Hyun, Shin, Jae-Gook
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862515/
https://ncbi.nlm.nih.gov/pubmed/26976869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02765-15
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