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Glucuronidation of trans-3′-hydroxycotinine by UGT2B17 and UGT2B10

trans-3′-Hydroxycotinine (3HC) and its glucuronide (3HC-Gluc) are major nicotine metabolites excreted in the urine of smokers and other tobacco users. While several members of the UDP-glucuronosyltransferase (UGT) family of enzymes were previously shown to be active in catalyzing the formation of 3H...

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Bibliografske podrobnosti
Main Authors: Chen, Gang, Giambrone, Nino E., Lazarus, Philip
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275669/
https://ncbi.nlm.nih.gov/pubmed/22228205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834ff3a5
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