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Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is an important tobacco-specific nitrosamine (TSNA) in the etiology of tobacco-related cancers, and N-glucuronidation is an important mechanism of NNAL detoxification. In the present study, an analysis of the UDP-glucuronosyltransferases (UGTs) re...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714266/ https://ncbi.nlm.nih.gov/pubmed/18238858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.107.019406 |
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