Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is an important tobacco-specific nitrosamine (TSNA) in the etiology of tobacco-related cancers, and N-glucuronidation is an important mechanism of NNAL detoxification. In the present study, an analysis of the UDP-glucuronosyltransferases (UGTs) re...

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Bibliografiske detaljer
Main Authors: Chen, Gang, Dellinger, Ryan W., Sun, Dongxiao, Spratt, Thomas E., Lazarus, Philip
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714266/
https://ncbi.nlm.nih.gov/pubmed/18238858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.107.019406
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