A carregar...

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants

INTRODUCTION: Tamoxifen (TAM) is an antiestrogen widely used in the treatment and prevention of breast cancer in women. One of the major mechanisms of metabolism of TAM and one of its major active metabolites, 4-hydroxytamoxifen (4-OH-TAM), is via glucuronidation. In the present study, the glucuroni...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sun, Dongxiao, Chen, Gang, Dellinger, Ryan W, Duncan, Kimberly, Fang, Jia-Long, Lazarus, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779459/
https://ncbi.nlm.nih.gov/pubmed/16884532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1539
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!