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Glucuronidation of trans-3′-hydroxycotinine by UGT2B17 and UGT2B10
trans-3′-Hydroxycotinine (3HC) and its glucuronide (3HC-Gluc) are major nicotine metabolites excreted in the urine of smokers and other tobacco users. While several members of the UDP-glucuronosyltransferase (UGT) family of enzymes were previously shown to be active in catalyzing the formation of 3H...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275669/ https://ncbi.nlm.nih.gov/pubmed/22228205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834ff3a5 |
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