Microbial marauders: pancreatic microbiota and its impact on carcinogenesis

Por Thomas, Ryan M., Zajac-Kaye, Maria
Publicado no Ann Transl Med (2018)

A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells

Por Zhang, Jianliang, He, Di-Hua, Zajac-Kaye, Maria, Hochwald, Steven N
Publicado no Cell Cycle (2014)

Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators

Por Yang, Hui, Salz, Tal, Zajac-Kaye, Maria, Liao, Daiqing, Huang, Suming, Qiu, Yi
Publicado em 2014

Current Understanding of the Molecular Biology of Pancreatic Neuroendocrine Tumors

Por Zhang, Jianliang, Francois, Rony, Iyer, Renuka, Seshadri, Mukund, Zajac-Kaye, Maria, Hochwald, Steven N.
Publicado no J Natl Cancer Inst (2013)

Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors

Por François, Rony A., Maeng, Kyungah, Nawab, Akbar, Kaye, Frederic J., Hochwald, Steven N., Zajac-Kaye, Maria
Publicado no J Natl Cancer Inst (2015)

Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A

Por CHEN, MIN, VOELLER, DONNA, MARQUEZ, VICTOR E., KAYE, FREDERIC J., STEEG, PATRICIA S., GIACCONE, GIUSEPPE, ZAJAC-KAYE, MARIA
Publicado no Int J Oncol (2010)

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer

Por Komiya, Takefumi, Coxon, Amy, Park, Yoonsoo, Chen, Wei-dong, Zajac-Kaye, Maria, Meltzer, Paul, Karpova, Tatiana, Kaye, Frederic J.
Publicado no Oncogene (2009)

Disruption of Myc-Tubulin Interaction by Hyperphosphorylation of c-Myc during Mitosis or by Constitutive Hyperphosphorylation of Mutant c-Myc in Burkitt's Lymphoma

Por Niklinski, Jacek, Claassen, Gisela, Meyers, Cheryl, Gregory, Mark A., Allegra, Carmen J., Kaye, Frederic J., Hann, Stephen R., Zajac-Kaye, Maria
Publicado em 2000

Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

Por Ucar, Deniz A., Magis, Andrew T., He, Di-Hua, Lawrence, Nicholas J., Sebti, Said M., Kurenova, Elena, Zajac-Kaye, Maria, Zhang, Jianliang, Hochwald, Steven N.
Publicado em 2013

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition

Por Gopalan, Priya K., Villegas, Andres Gordillo, Cao, Chunxia, Pinder-Schenck, Mary, Chiappori, Alberto, Hou, Wei, Zajac-Kaye, Maria, Ivey, Alison M., Kaye, Frederic J.
Publicado no Oncotarget (2018)

Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent

Por Nguyen, Diana, Zajac-Kaye, Maria, Rubinstein, Larry, Voeller, Donna, Tomaszewski, Joseph E, Kummar, Shivaani, Chen, Alice P, Pommier, Yves, Doroshow, James H, Yang, Sherry X
Publicado em 2011

NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations

Por Narayan, Satya, Jaiswal, Aruna S., Sharma, Ritika, Nawab, Akbar, Duckworth, Lizette Vila, Law, Brian K., Zajac-Kaye, Maria, George, Thomas J., Sharma, Jay, Sharma, Arun K., Hromas, Robert A.
Publicado no Oncotarget (2017)

Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth

Por Ucar, Deniz A., Kurenova, Elena, Garrett, Timothy J., Cance, William G., Nyberg, Carl, Cox, Audrey, Massoll, Nicole, Ostrov, David A., Lawrence, Nicholas, Sebti, Said M., Zajac-Kaye, Maria, Hochwald, Steven N.
Publicado em 2012

Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors

Por Chen, Min, Maeng, Kyungah, Nawab, Akbar, Francois, Rony A., Bray, Julie K., Reinhard, Mary K., Boye, Sanford L., Hauswirth, William W., Kaye, Frederic J., Aslanidi, Georgiy, Srivastava, Arun, Zajac-Kaye, Maria
Publicado no Hum Gene Ther Methods (2017)

DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer

Por Chen, Min, Shabashvili, Daniel, Nawab, Akbar, Yang, Sherry X., Dyer, Lisa M., Brown, Kevin D., Hollingshead, Melinda, Hunter, Kent W., Kaye, Frederic J., Hochwald, Steven N., Marquez, Victor E., Steeg, Patricia, Zajac-Kaye, Maria
Publicado no Mol Cancer Ther (2011)

CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB–MYC involvement

Por Amelio, Antonio L., Fallahi, Mohammad, Schaub, Franz X., Zhang, Min, Lawani, Mariam B., Alperstein, Adam S., Southern, Mark R., Young, Brandon M., Wu, Lizi, Zajac-Kaye, Maria, Kaye, Frederic J., Cleveland, John L., Conkright, Michael D.
Publicado em 2014

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

Por Gao, Ruli, Cao, Chunxia, Zhang, Min, Lopez, Maria-Cecilia, Yan, Yuanqing, Chen, Zirong, Mitani, Yoshitsugu, Zhang, Li, Zajac-Kaye, Maria, Liu, Bin, Wu, Lizi, Renne, Rolf, Baker, Henry V., El-Naggar, Adel, Kaye, Frederic J.
Publicado no Oncotarget (2014)

Role of LKB1-CRTC1 on Glycosylated COX-2 and Response to COX-2 Inhibition in Lung Cancer

Por Cao, Chunxia, Gao, Ruli, Zhang, Min, Amelio, Antonio L., Fallahi, Mohammad, Chen, Zirong, Gu, Yumei, Hu, Chengbin, Welsh, Eric A., Engel, Brienne E., Haura, Eric B., Cress, W. Douglas, Wu, Lizi, Zajac-Kaye, Maria, Kaye, Frederic J.
Publicado no J Natl Cancer Inst (2014)

MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma

Por Jiang, Yue, Gao, Ruli, Cao, Chunxia, Forbes, Lauren, Li, Jianping, Freeberg, Shelby, Fredenburg, Kristianna M, Justice, Jeb M., Silver, Natalie L, Wu, Lizi, Varma, Sushama, West, Robert, Licht, Jonathan D., Zajac-Kaye, Maria, Kentsis, Alex, Kaye, Frederic J.
Publicado no Oral Oncol (2019)

Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models

Por Thomas, Ryan M, Gharaibeh, Raad Z, Gauthier, Josee, Beveridge, Mark, Pope, Jillian L, Guijarro, Maria V, Yu, Qin, He, Zhen, Ohland, Christina, Newsome, Rachel, Trevino, Jose, Hughes, Steven J, Reinhard, Mary, Winglee, Kathryn, Fodor, Anthony A, Zajac-Kaye, Maria, Jobin, Christian
Publicado no Carcinogenesis (2018)