Unraveling Breast Cancer Heterogeneity Through Transcriptomic and Epigenomic Analysis

Por Orlando, Frank A., Brown, Kevin D.
Publicado em 2009

Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents

Por Izumchenko, Eugene, Saydi, John, Brown, Kevin D.
Publicado em 2012

Differential Signaling and Tumor Necrosis Factor Receptor–Associated Factor (Traf) Degradation Mediated by Cd40 and the Epstein-Barr Virus Oncoprotein Latent Membrane Protein 1 (Lm...

Por Brown, Kevin D., Hostager, Bruce S., Bishop, Gail A.
Publicado em 2001

Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ Light Chain Enhancer of Activated B Cells (NFκB) Signaling Controls Basal and DNA Damage-induced Transglutaminase 2 Expression...

Por Ai, Lingbao, Skehan, Ryan R., Saydi, John, Lin, Tong, Brown, Kevin D.
Publicado em 2012

The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2/M checkpoint

Por Jiang, Zhihua, Jin, ShunQian, Yalowich, Jack C., Brown, Kevin D., Baskaran, R.
Publicado em 2010

DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B

Por Palii, Stela S., Van Emburgh, Beth O., Sankpal, Umesh T., Brown, Kevin D., Robertson, Keith D.
Publicado em 2008

TLR9 engagement on CD4 T lymphocytes represses γ-radiation–induced apoptosis through activation of checkpoint kinase response elements

Por Zheng, Liqin, Asprodites, Nicole, Keene, Angela H., Rodriguez, Paulo, Brown, Kevin D., Davila, Eduardo
Publicado em 2008

Bisulfite Sequencing of DNA

Por Darst, Russell P., Pardo, Carolina E., Ai, Lingbao, Brown, Kevin D., Kladde, Michael P.
Publicado em 2010

Methylator-induced, Mismatch Repair-dependent G(2) Arrest Is Activated through Chk1 and Chk2

Por Adamson, Aaron W., Beardsley, Dillon I., Kim, Wan-Ju, Gao, Yajuan, Baskaran, R., Brown, Kevin D.
Publicado em 2005

Comparative Epigenomics of Human and Mouse Mammary Tumors

Por Demircan, Berna, Dyer, Lisa M., Gerace, Mallory, Lobenhofer, Edward K., Robertson, Keith D., Brown, Kevin D.
Publicado em 2009

Quantitative DNA Methylation Analysis of Candidate Genes in Cervical Cancer

Por Siegel, Erin M., Riggs, Bridget M., Delmas, Amber L., Koch, Abby, Hakam, Ardeshir, Brown, Kevin D.
Publicado no PLoS One (2015)

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

Por Brown, Kevin D., Ziv, Yael, Sadanandan, Sunanda N., Chessa, Luciana, Collins, Francis S., Shiloh, Yosef, Tagle, Danilo A.
Publicado em 1997

NAD(+) and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents

Por Harkcom, William T., Ghosh, Ananda K., Sung, Matthew S., Matov, Alexandre, Brown, Kevin D., Giannakakou, Paraskevi, Jaffrey, Samie R.
Publicado em 2014

The transglutaminase 2 gene is aberrantly hypermethylated in glioma

Por Dyer, Lisa M., Schooler, Kevin P., Ai, Lingbao, Klop, Corinne, Qiu, Jingxin, Robertson, Keith D., Brown, Kevin D.
Publicado em 2010

PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice

Por Cheng, Xiaodong, Byrne, Michael, Brown, Kevin D., Konopleva, Marina Y., Kornblau, Steven M., Bennett, Richard L., May, W. Stratford
Publicado no Blood (2015)

Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery

Por Ha, Kyungsoo, Lee, Gun Eui, Palii, Stela S., Brown, Kevin D., Takeda, Yoshihiko, Liu, Kebin, Bhalla, Kapil N., Robertson, Keith D.
Publicado em 2011

CENP-E is an essential kinetochore motor in maturing oocytes and is masked during Mos-dependent, cell cycle arrest at metaphase II

Por Duesbery, Nick S., Choi, Taesaeng, Brown, Kevin D., Wood, Kenneth W., Resau, James, Fukasawa, Kenji, Cleveland, Don W., Vande Woude, George F.
Publicado em 1997

Activation of SIRT3 by the NAD(+) precursor nicotinamide riboside protects from noise-induced hearing loss

Por Brown, Kevin D., Maqsood, Sadia, Huang, Jing-Yi, Pan, Yong, Harkcom, William, Li, Wei, Sauve, Anthony, Verdin, Eric, Jaffrey, Samie R.
Publicado no Cell Metab (2014)

The Breast Cancer Tumor Suppressor TRIM29 Is Expressed via ATM-dependent Signaling in Response to Hypoxia

Por Dükel, Muzaffer, Streitfeld, W. Scott, Tang, Tsz Ching Chloe, Backman, Lindsey R. F., Ai, Lingbao, May, W. Stratford, Brown, Kevin D.
Publicado no J Biol Chem (2016)

Sonic Hedgehog Is An Autocrine Viability Factor for Myofibroblastic Hepatic Stellate Cells

Por Yang, Liu, Wang, Ying, Mao, Hua, Fleig, Susanne, Omenetti, Alessia, Brown, Kevin D., Sicklick, Jason K, Li, Yin-Xiong, Diehl, Anna Mae
Publicado em 2007