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MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma

OBJECTIVE: There are no effective systemic therapies for adenoid cystic cancer (ACC) and lack of tumor lines and mouse models have hindered drug development. We aim to develop MYB-activated models for testing new therapeutic agents. MATERIALS AND METHODS: We studied new ACC patient-derived xenograft...

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Detalhes bibliográficos
Publicado no:Oral Oncol
Main Authors: Jiang, Yue, Gao, Ruli, Cao, Chunxia, Forbes, Lauren, Li, Jianping, Freeberg, Shelby, Fredenburg, Kristianna M, Justice, Jeb M., Silver, Natalie L, Wu, Lizi, Varma, Sushama, West, Robert, Licht, Jonathan D., Zajac-Kaye, Maria, Kentsis, Alex, Kaye, Frederic J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184536/
https://ncbi.nlm.nih.gov/pubmed/31606723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2019.09.005
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