CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB–MYC involvement

Chimeric oncoproteins created by chromosomal translocations are among the most common genetic mutations associated with tumorigenesis. Malignant mucoepidermoid salivary gland tumors, as well as a growing number of solid epithelial-derived tumors, can arise from a recurrent t (11, 19)(q21;p13.1) tran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Amelio, Antonio L., Fallahi, Mohammad, Schaub, Franz X., Zhang, Min, Lawani, Mariam B., Alperstein, Adam S., Southern, Mark R., Young, Brandon M., Wu, Lizi, Zajac-Kaye, Maria, Kaye, Frederic J., Cleveland, John L., Conkright, Michael D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136562/
https://ncbi.nlm.nih.gov/pubmed/25071166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319176111
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