Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

Pancreatic cancer is one of the most lethal diseases with no effective treatment. Previously, we have shown that FAK is overexpressed in pancreatic cancer and plays a key role in cancer cell survival and proliferation. FAK has been shown to interact with growth factor receptors including cMET and IG...

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Bibliographic Details
Main Authors:	Ucar, Deniz A., Magis, Andrew T., He, Di-Hua, Lawrence, Nicholas J., Sebti, Said M., Kurenova, Elena, Zajac-Kaye, Maria, Zhang, Jianliang, Hochwald, Steven N.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4052463/ https://ncbi.nlm.nih.gov/pubmed/23272972
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Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

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