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FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

Pancreatic cancer is a lethal disease accounting for the fourth leading cause of cancer death in USA. Focal adhesion kinase (FAK) and the insulin-like growth factor-I receptor (IGF-1R) are tyrosine kinases that activate common pathways, leading to increased proliferation and cell survival. Sparse in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Weiguo, Bloom, David A., Cance, William G., Kurenova, Elena V., Golubovskaya, Vita M., Hochwald, Steven N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902396/
https://ncbi.nlm.nih.gov/pubmed/18263593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn026
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