A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

MYB activation is proposed to underlie development of adenoid cystic cancer (ACC), an aggressive salivary gland tumor with no effective systemic treatments. To discover druggable targets for ACC, we performed global mRNA/miRNA analyses of 12 ACC with matched normal tissues, and compared these data w...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Gao, Ruli, Cao, Chunxia, Zhang, Min, Lopez, Maria-Cecilia, Yan, Yuanqing, Chen, Zirong, Mitani, Yoshitsugu, Zhang, Li, Zajac-Kaye, Maria, Liu, Bin, Wu, Lizi, Renne, Rolf, Baker, Henry V., El-Naggar, Adel, Kaye, Frederic J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
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Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350357/
https://ncbi.nlm.nih.gov/pubmed/25587024
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