Novel Chromosomal Rearrangements and breakpoints at the t(6;9) in Salivary Adenoid Cystic Carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome

OBJECTIVE: To investigate the molecular-genetic heterogeneity associated with the t(6:9) in adenoid cystic carcinoma (ACC) and correlate the findings with patient clinical outcome. EXPERIMENTAL DESIGN: Multi-molecular and genetic techniques complemented with massive pair-ended sequencing and SNP arr...

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Detalhes bibliográficos
Main Authors: Mitani, Yoshitsugu, Rao, Pulivarthi H., Futreal, P. Andrew, Roberts, Dianna B., Stephens, Philip J., Zhao, Yi-Jue, Zhang, Li, Mitani, Mutsumi, Weber, Randal S., Lippman, Scott M., Caulin, Carlos, El-Naggar, Adel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225955/
https://ncbi.nlm.nih.gov/pubmed/21976542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1870
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