Novel MYBL1 gene rearrangements with recurrent MYBL1-NFIB fusions in salivary adenoid cystic carcinomas lacking t(6;9) translocations

PURPOSE: Adenoid cystic carcinoma (ACC) is an indolent salivary gland malignancy, characterized by t(6;9) translocations and MYB-NFIB gene fusions in approximately 50% of the tumors. The genetic alterations underlying t(6;9)-negative and t(6;9)-positive/MYB-NFIB-fusion negative ACC remain unknown. T...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Mitani, Yoshitsugu, Liu, Bin, Rao, Pulivarthi H., Borra, Vishnupriya J, Zafereo, Mark, Weber, Randal S., Kies, Merrill, Lozano, Guillermina, Futreal, P. Andrew, Caulin, Carlos, El-Naggar, Adel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807116/
https://ncbi.nlm.nih.gov/pubmed/26631609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2867-T
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