Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma

Adenoid cystic carcinoma (ACC) is the second most common cancer type arising from the salivary gland. The frequent occurrence of chromosome t(6;9) translocation leading to the fusion of MYB and NFIB transcription factor genes is considered a genetic hallmark of ACC. This inter-chromosomal rearrangem...

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Autori principali: Joseph O. Humtsoe, Hyun-Su Kim, Leilani Jones, James Cevallos, Philippe Boileau, Fengshen Kuo, Luc G. T. Morris, Patrick Ha
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-04-01
Serie:Cancers
Soggetti:
adenoid cystic carcinoma
chromosomal t(6
9) translocation
MYB
MYB-NFIB fusion
Accesso online:https://www.mdpi.com/2072-6694/14/9/2263
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