Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses

per Nishimura, Yasuharu, Tomita, Yusuke, Yuno, Akira, Yoshitake, Yoshihiro, Shinohara, Masanori
Publicat a Cancer Sci (2015)

Immunotherapy: a new treatment paradigm in bladder cancer

per Davarpanah, Nicole N., Yuno, Akira, Trepel, Jane B., Apolo, Andrea B.
Publicat a Curr Opin Oncol (2017)

Generation of Large Numbers of Antigen-Expressing Human Dendritic Cells Using CD14-ML Technology

per Imamura, Yuya, Haruta, Miwa, Tomita, Yusuke, Matsumura, Keiko, Ikeda, Tokunori, Yuno, Akira, Hirayama, Masatoshi, Nakayama, Hideki, Mizuta, Hiroshi, Nishimura, Yasuharu, Senju, Satoru
Publicat a PLoS One (2016)

In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical be...

per Tomita, Yusuke, Oronsky, Bryan, Abrouk, Nacer, Cabrales, Pedro, Reid, Tony R., Lee, Min-Jung, Yuno, Akira, Baker, Jonathan, Lee, Sunmin, Trepel, Jane B.
Publicat a Transl Lung Cancer Res (2021)

Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response

per Sayem, Mohammad A., Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Irie, Atsushi, Tsukamoto, Hirotake, Senju, Satoru, Yuba, Eiji, Yoshikawa, Toshiaki, Kono, Kenji, Nakatsura, Tetsuya, Nishimura, Yasuharu
Publicat a Oncoimmunology (2015)

Clinical outcomes of prexasertib monotherapy in recurrent BRCA wild-type high-grade serous ovarian cancer involve innate and adaptive immune responses

per Lampert, Erika J, Cimino-Mathews, Ashley, Lee, Joo Sang, Nair, Jayakumar, Lee, Min-Jung, Yuno, Akira, An, Daniel, Trepel, Jane B, Ruppin, Eytan, Lee, Jung-Min
Publicat a J Immunother Cancer (2020)

A Phase II Single Arm Pilot Study of the CHK1 Inhibitor Prexasertib (LY2606368) in BRCA Wild‐Type, Advanced Triple‐Negative Breast Cancer

per Gatti‐Mays, Margaret E., Karzai, Fatima H., Soltani, Sanaz N., Zimmer, Alexandra, Green, Jeffrey E., Lee, Min‐Jung, Trepel, Jane B., Yuno, Akira, Lipkowitz, Stanley, Nair, Jayakumar, McCoy, Ann, Lee, Jung‐Min
Publicat a Oncologist (2020)

Phase I/II Study of the Mesothelin-targeted Immunotoxin LMB-100 with Nab-Paclitaxel for Patients with Advanced Pancreatic Adenocarcinoma

per Alewine, Christine, Ahmad, Mehwish, Peer, Cody J., Hu, Zishuo I., Lee, Min-Jung, Yuno, Akira, Kindrick, Jessica D., Thomas, Anish, Steinberg, Seth M., Trepel, Jane B., Figg, William D., Hassan, Raffit, Pastan, Ira
Publicat a Clin Cancer Res (2019)

Patients with BRCA mutated ovarian cancer may have fewer circulating MDSC and more peripheral CD8(+) T cells compared with women with BRCA wild-type disease during the early diseas...

per Lee, Jung-Min, Botesteanu, Dana-Adriana, Tomita, Yusuke, Yuno, Akira, Lee, Min-Jung, Kohn, Elise C., Annunziata, Christina M., Matulonis, Ursula, MacDonald, Lauren A., Nair, Jayakumar R., Macneill, Kimberley M., Trepel, Jane B.
Publicat a Oncol Lett (2019)

Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens

per Yatsuda, Junji, Irie, Atsushi, Harada, Kumiko, Michibata, Yayoi, Tsukamoto, Hirotake, Senju, Satoru, Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Abu Sayem, Mohammad, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Fujiki, Fumihiro, Sugiyama, Haruo, Eto, Masatoshi, Nishimura, Yasuharu
Publicat 2013

An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs

per Hirayama, Masatoshi, Tomita, Yusuke, Yuno, Akira, Tsukamoto, Hirotake, Senju, Satoru, Imamura, Yuya, Sayem, Mohammad Abu, Irie, Atsushi, Yoshitake, Yoshihiro, Fukuma, Daiki, Shinohara, Masanori, Hamada, Akinobu, Jono, Hirofumi, Yuba, Eiji, Kono, Kenji, Yoshida, Koji, Tsunoda, Takuya, Nakayama, Hideki, Nishimura, Yasuharu
Publicat a Oncoimmunology (2016)

Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease

per Tomita, Yusuke, Yuno, Akira, Tsukamoto, Hirotake, Senju, Satoru, Kuroda, Yasuhiro, Hirayama, Masatoshi, Imamura, Yuya, Yatsuda, Junji, Sayem, Mohammad Abu, Irie, Atsushi, Hamada, Akinobu, Jono, Hirofumi, Yoshida, Koji, Tsunoda, Takuya, Daigo, Yataro, Kohrogi, Hirotsugu, Yoshitake, Yoshihiro, Nakamura, Yusuke, Shinohara, Masanori, Nishimura, Yasuharu
Publicat 2014

Entinostat plus pembrolizumab in patients with metastatic NSCLC previously treated with anti-PD-(L)1 therapy

per Hellmann, Matthew D., Jänne, Pasi A., Opyrchal, Mateusz, Hafez, Navid, Raez, Luis E., Gabrilovich, Dmitry, Wang, Fang, Trepel, Jane B., Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Brouwer, Susan, Sankoh, Serap, Wang, Lei, Tamang, David, Schmidt, Emmett, Meyers, Michael L., Ramalingam, Suresh S., Shum, Elaine, Ordentlich, Peter
Publicat a Clin Cancer Res (2020)

Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors

per Thomas, Anish, Redon, Christophe E., Sciuto, Linda, Padiernos, Emerson, Ji, Jiuping, Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Zhang, Yiping, Tran, Lan, Yutzy, William, Rajan, Arun, Guha, Udayan, Chen, Haobin, Hassan, Raffit, Alewine, Christine C., Szabo, Eva, Bates, Susan E., Kinders, Robert J., Steinberg, Seth M., Doroshow, James H., Aladjem, Mirit I., Trepel, Jane B., Pommier, Yves
Publicat a J Clin Oncol (2018)

Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations

per Karzai, Fatima, VanderWeele, David, Madan, Ravi A., Owens, Helen, Cordes, Lisa M., Hankin, Amy, Couvillon, Anna, Nichols, Erin, Bilusic, Marijo, Beshiri, Michael L., Kelly, Kathleen, Krishnasamy, Venkatesh, Lee, Sunmin, Lee, Min-Jung, Yuno, Akira, Trepel, Jane B., Merino, Maria J., Dittamore, Ryan, Marté, Jennifer, Donahue, Renee N., Schlom, Jeffrey, Killian, Keith J., Meltzer, Paul S., Steinberg, Seth M., Gulley, James L., Lee, Jung-Min, Dahut, William L.
Publicat a J Immunother Cancer (2018)

Cabozantinib plus docetaxel and prednisone in metastatic castration-resistant prostate cancer

per Madan, Ravi A., Karzai, Fatima H., Harthy, Munjid Al, Petrylak, Daniel P., Kim, Joseph W., Arlen, Philip M., Rosner, Inger, Theoret, Marc R., Cordes, Lisa, Bilusic, Marijo, Peer, Cody J., Dawson, Nancy A., Couvillon, Anna, Hankin, Amy, Williams, Moniquea, Chun, Guin, Owens, Helen, Marte, Jennifer L., Lee, Min-Jung, Tomita, Yusuke, Yuno, Akira, Trepel, Jane B., Lee, Sunmin, Steinberg, Seth M., Gulley, James L., Figg, William D., Dahut, William L.
Publicat a BJU Int (2020)

Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study

per Burke, Michael J., Kostadinov, Rumen, Sposto, Richard, Gore, Lia, Kelley, Shannon, Rabik, Cara, Trepel, Jane, Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Bhojwani, Deepa, Jeha, Sima C., Chang, Bill H., Sulis, Maria Luisa, Hermiston, Michelle L., Gaynon, Paul S., Huynh, Van, Verma, Anupam, Gardner, Rebecca A., Heym, Kenneth M., Dennis, Robyn M., Ziegler, David S., Laetsch, Theodore W., Oesterheld, Javier E., DuBois, Steven G., Pollard, Jessica A., Glade-Bender, Julia, Cooper, Todd M., Kaplan, Joel A., Farooqi, Midhat, Yoo, Byunggil, Guest, Erin, Wayne, Alan S., Brown, Patrick
Publicat a Clin Cancer Res (2020)

Cabozantinib and peripheral immunity in advanced urothelial carcinoma: Final results from an open-label, phase II trial

per Apolo, Andrea B., Nadal, Rosa, Tomita, Yusuke, Davarpanah, Nicole N., Cordes, Lisa M., Steinberg, Seth M., Cao, Liang, Parnes, Howard L., Costello, Rene, Merino, Maria J., Folio, Les R., Lindenberg, Liza, Raffeld, Mark, Lin, Jeffrey, Lee, Min-Jung, Lee, Sunmin, Alarcon, Sylvia V., Yuno, Akira, Dawson, Nancy A., Allette, Kimaada, Roy, Arpita, De Silva, Dinuka, Lee, Molly M., Sissung, Tristan M., Figg, William D., Agarwal, Piyush K., Wright, John J., Ning, Yangmin M., Gulley, James L., Dahut, William L., Bottaro, Donald P., Trepel, Jane B.
Publicat a Lancet Oncol (2020)

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

per Oshima, Nobu, Ishida, Ryo, Kishimoto, Shun, Beebe, Kristin, Brender, Jeffrey R., Yamamoto, Kazutoshi, Urban, Daniel, Rai, Ganesha, Johnson, Michelle S., Benavides, Gloria, Squadrito, Giuseppe L., Crooks, Dan, Jackson, Joseph, Joshi, Abhinav, Mott, Bryan T., Shrimp, Jonathan H., Moses, Michael A., Lee, Min-Jung, Yuno, Akira, Lee, Tobie D., Hu, Xin, Anderson, Tamara, Kusewitt, Donna, Hathaway, Helen H., Jadhav, Ajit, Picard, Didier, Trepel, Jane B., Mitchell, James B., Stott, Gordon M., Moore, William, Simeonov, Anton, Sklar, Larry A., Norenberg, Jeffrey P., Linehan, W. Marston, Maloney, David J., Dang, Chi V., Waterson, Alex G., Hall, Matthew, Darley-Usmar, Victor M., Krishna, Murali C., Neckers, Leonard M.
Publicat a Cell Rep (2020)

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

per Thomas, Anish, Takahashi, Nobuyuki, Rajapakse, Vinodh N., Zhang, Xiaohu, Sun, Yilun, Ceribelli, Michele, Wilson, Kelli M., Zhang, Yang, Beck, Erin, Sciuto, Linda, Nichols, Samantha, Elenbaas, Brian, Puc, Janusz, Dahmen, Heike, Zimmermann, Astrid, Varonin, Jillian, Schultz, Christopher W., Kim, Sehyun, Shimellis, Hirity, Desai, Parth, Klumpp-Thomas, Carleen, Chen, Lu, Travers, Jameson, McKnight, Crystal, Michael, Sam, Itkin, Zina, Lee, Sunmin, Yuno, Akira, Lee, Min-Jung, Redon, Christophe E., Kindrick, Jessica D., Peer, Cody J., Wei, Jun S., Aladjem, Mirit I., Figg, William Douglas, Steinberg, Seth M., Trepel, Jane B., Zenke, Frank T., Pommier, Yves, Khan, Javed, Thomas, Craig J.
Publicat a Cancer Cell (2021)