Modeling the Effect of Hypoxia and DNA Repair Inhibition on Cell Survival after Photon Irradiation

por Liew, Hans, Klein, Carmen, Zenke, Frank T., Abdollahi, Amir, Debus, Jürgen, Dokic, Ivana, Mairani, Andrea
Publicado en Int J Mol Sci (2019)

DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia

por Carr, Michael I., Zimmermann, Astrid, Chiu, Li-Ya, Zenke, Frank T., Blaukat, Andree, Vassilev, Lyubomir T.
Publicado en Front Oncol (2020)

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

por Orth, James D., Tang, Yangzhong, Shi, Jade, Loy, Clement T., Amendt, Christiane, Wilm, Claudia, Zenke, Frank T., Mitchison, Timothy J.
Publicado 2008

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

por Roidos, Paris, Sungalee, Stephanie, Benfatto, Salvatore, Serçin, Özdemirhan, Stütz, Adrian M., Abdollahi, Amir, Mauer, Jan, Zenke, Frank T., Korbel, Jan O., Mardin, Balca R.
Publicado en Nat Commun (2020)

DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia

por Haines, Eric, Nishida, Yuki, Carr, Michael I., Montoya, Rafael Heinz, Ostermann, Lauren B., Zhang, Weiguo, Zenke, Frank T., Blaukat, Andree, Andreeff, Michael, Vassilev, Lyubomir T.
Publicado en Sci Rep (2021)

Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation

por Klein, Carmen, Dokic, Ivana, Mairani, Andrea, Mein, Stewart, Brons, Stephan, Häring, Peter, Haberer, Thomas, Jäkel, Oliver, Zimmermann, Astrid, Zenke, Frank, Blaukat, Andree, Debus, Jürgen, Abdollahi, Amir
Publicado en Radiat Oncol (2017)

A solid‐phase transfection platform for arrayed CRISPR screens

por Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z, Abdollahi, Amir, Zenke, Frank T, Neumann, Beate, Mardin, Balca R
Publicado en Mol Syst Biol (2019)

A solid‐phase transfection platform for arrayed CRISPR screens

por Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z, Abdollahi, Amir, Zenke, Frank T, Neumann, Beate, Mardin, Balca R
Publicado en Mol Syst Biol (2020)

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

por Thomas, Anish, Takahashi, Nobuyuki, Rajapakse, Vinodh N., Zhang, Xiaohu, Sun, Yilun, Ceribelli, Michele, Wilson, Kelli M., Zhang, Yang, Beck, Erin, Sciuto, Linda, Nichols, Samantha, Elenbaas, Brian, Puc, Janusz, Dahmen, Heike, Zimmermann, Astrid, Varonin, Jillian, Schultz, Christopher W., Kim, Sehyun, Shimellis, Hirity, Desai, Parth, Klumpp-Thomas, Carleen, Chen, Lu, Travers, Jameson, McKnight, Crystal, Michael, Sam, Itkin, Zina, Lee, Sunmin, Yuno, Akira, Lee, Min-Jung, Redon, Christophe E., Kindrick, Jessica D., Peer, Cody J., Wei, Jun S., Aladjem, Mirit I., Figg, William Douglas, Steinberg, Seth M., Trepel, Jane B., Zenke, Frank T., Pommier, Yves, Khan, Javed, Thomas, Craig J.
Publicado en Cancer Cell (2021)