Novel roles for JNK1 in metabolism

par Belgardt, Bengt F., Mauer, Jan, Brüning, Jens C.
Publié 2010

Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF-κB Activation in Macrophages

par Chaurasia, Bhagirath, Mauer, Jan, Koch, Linda, Goldau, Julia, Kock, Anja-Sterner, Brüning, Jens C.
Publié 2010

Hierarchical prediction errors in midbrain and septum during social learning

par Diaconescu, Andreea O., Mathys, Christoph, Weber, Lilian A. E., Kasper, Lars, Mauer, Jan, Stephan, Klaas E.
Publié dans Soc Cogn Affect Neurosci (2017)

Single copy shRNA configuration for ubiquitous gene knockdown in mice

par Seibler, Jost, Küter-Luks, Birgit, Kern, Heidrun, Streu, Sandra, Plum, Leona, Mauer, Jan, Kühn, Ralf, Brüning, Jens C., Schwenk, Frieder
Publié 2005

Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance

par Mauer, Jan, Chaurasia, Bhagirath, Plum, Leona, Quast, Thomas, Hampel, Brigitte, Blüher, Matthias, Kolanus, Waldemar, Kahn, C. Ronald, Brüning, Jens C.
Publié 2010

MyD88 signaling in the CNS is required for development of fatty acid induced leptin resistance and diet-induced obesity

par Kleinridders, André, Schenten, Dominik, Könner, A. Christine, Belgardt, Bengt F., Mauer, Jan, Okamura, Tomoo, Wunderlich, F. Thomas, Medzhitov, Ruslan, Brüning, Jens C.
Publié 2009

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

par Roidos, Paris, Sungalee, Stephanie, Benfatto, Salvatore, Serçin, Özdemirhan, Stütz, Adrian M., Abdollahi, Amir, Mauer, Jan, Zenke, Frank T., Korbel, Jan O., Mardin, Balca R.
Publié dans Nat Commun (2020)

Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism

par Belgardt, Bengt F., Mauer, Jan, Wunderlich, F. Thomas, Ernst, Marianne B., Pal, Martin, Spohn, Gabriele, Brönneke, Hella S., Brodesser, Susanne, Hampel, Brigitte, Schauss, Astrid C., Brüning, Jens C.
Publié 2010

FTO controls reversible m(6)Am RNA methylation during snRNA biogenesis

par Mauer, Jan, Sindelar, Miriam, Despic, Vladimir, Guez, Théo, Hawley, Ben R., Vasseur, Jean-Jacques, Rentmeister, Andrea, Gross, Steven S., Pellizzoni, Livio, Debart, Françoise, Goodarzi, Hani, Jaffrey, Samie R.
Publié dans Nat Chem Biol (2019)

An Obesity-Predisposing Variant of the FTO Gene Regulates D2R-Dependent Reward Learning

par Sevgi, Meltem, Rigoux, Lionel, Kühn, Anne B., Mauer, Jan, Schilbach, Leonhard, Hess, Martin E., Gruendler, Theo O.J., Ullsperger, Markus, Stephan, Klaas Enno, Brüning, Jens C., Tittgemeyer, Marc
Publié dans J Neurosci (2015)

Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high fat feeding

par Vogt, Merly C., Paeger, Lars, Hess, Simon, Steculorum, Sophie M., Awazawa, Motoharu, Hampel, Brigitte, Neupert, Susanne, Nicholls, Hayley T., Mauer, Jan, Hausen, A. Christine, Predel, Reinhard, Kloppenburg, Peter, Horvath, Tamas L., Brüning, Jens C.
Publié 2014

Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

par Wunderlich, Claudia M., Ackermann, P. Justus, Ostermann, Anna Lena, Adams-Quack, Petra, Vogt, Merly C., Tran, My-Ly, Nikolajev, Alexei, Waisman, Ari, Garbers, Christoph, Theurich, Sebastian, Mauer, Jan, Hövelmeyer, Nadine, Wunderlich, F. Thomas
Publié dans Nat Commun (2018)

Reversible methylation of m(6)A(m) in the 5′ cap controls mRNA stability

par Mauer, Jan, Luo, Xiaobing, Blanjoie, Alexandre, Jiao, Xinfu, Grozhik, Anya V., Patil, Deepak P., Linder, Bastian, Pickering, Brian F., Vasseur, Jean-Jacques, Chen, Qiuying, Gross, Steven S., Elemento, Olivier, Debart, Françoise, Kiledjian, Megerditch, Jaffrey, Samie R.
Publié dans Nature (2016)

Loss of UCP2 Attenuates Mitochondrial Dysfunction without Altering ROS Production and Uncoupling Activity

par Kukat, Alexandra, Dogan, Sukru Anil, Edgar, Daniel, Mourier, Arnaud, Jacoby, Christoph, Maiti, Priyanka, Mauer, Jan, Becker, Christina, Senft, Katharina, Wibom, Rolf, Kudin, Alexei P., Hultenby, Kjell, Flögel, Ulrich, Rosenkranz, Stephan, Ricquier, Daniel, Kunz, Wolfram S., Trifunovic, Aleksandra
Publié 2014

Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance

par Bailly-Maitre, Béatrice, Belgardt, Bengt F., Jordan, Sabine D., Coornaert, Beatrice, John von Freyend, Miriam, Kleinridders, Andre, Mauer, Jan, Cuddy, Michael, Kress, Christina L., Willmes, Diana, Essig, Manuela, Hampel, Brigitte, Protzer, Ulrike, Reed, John C., Brüning, Jens C.
Publié 2010

Interleukin-6 signaling promotes alternative macrophage activation to limit obesity-associated insulin resistance and endotoxemia

par Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C., Ruud, Johan, Nguyen, Khoa D., Theurich, Sebastian, Hausen, A. Christine, Schmitz, Joel, Brönneke, Hella S., Estevez, Emma, Allen, Tamara L., Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A., Chawla, Ajay, Wunderlich, F. Thomas, Brüning, Jens C.
Publié 2014

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

par Steculorum, Sophie M., Ruud, Johan, Karakasilioti, Ismene, Backes, Heiko, Ruud, Linda Engström, Timper, Katharina, Hess, Martin E., Tsaousidou, Eva, Mauer, Jan, Vogt, Merly C., Paeger, Lars, Bremser, Stephan, Klein, Andreas C., Morgan, Donald A., Frommolt, Peter, Brinkkötter, Paul T., Hammerschmidt, Philipp, Benzing, Thomas, Rahmouni, Kamal, Wunderlich, F. Thomas, Kloppenburg, Peter, Brüning, Jens C.
Publié dans Cell (2016)