Insulin Receptor Signaling in Normal and Insulin-Resistant States

Por Boucher, Jérémie, Kleinridders, André, Kahn, C. Ronald
Publicado em 2014

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

Por Kleinridders, André, Ferris, Heather A., Cai, Weikang, Kahn, C. Ronald
Publicado em 2014

Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activity

Por Vienberg, Sara Gry, Kleinridders, André, Suzuki, Ryo, Kahn, C. Ronald
Publicado no Mol Metab (2014)

Reversible gene knockdown in mice using a tight, inducible shRNA expression system

Por Seibler, Jost, Kleinridders, Andre, Küter-Luks, Birgit, Niehaves, Sandra, Brüning, Jens C., Schwenk, Frieder
Publicado em 2007

PLRG1 Is an Essential Regulator of Cell Proliferation and Apoptosis during Vertebrate Development and Tissue Homeostasis

Por Kleinridders, André, Pogoda, Hans-Martin, Irlenbusch, Sigrid, Smyth, Neil, Koncz, Csaba, Hammerschmidt, Matthias, Brüning, Jens C.
Publicado em 2009

Leptin regulation of Hsp60 impacts hypothalamic insulin signaling

Por Kleinridders, André, Lauritzen, Hans P.M.M., Ussar, Siegfried, Christensen, Jane H., Mori, Marcelo A., Bross, Peter, Kahn, C. Ronald
Publicado em 2013

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Por Boucher, Jeremie, Charalambous, Marika, Zarse, Kim, Mori, Marcelo A., Kleinridders, Andre, Ristow, Michael, Ferguson-Smith, Anne C., Kahn, C. Ronald
Publicado em 2014

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

Por Kleinridders, Andre, Cai, Weikang, Cappellucci, Laura, Ghazarian, Armen, Collins, William R., Vienberg, Sara G., Pothos, Emmanuel N., Kahn, C. Ronald
Publicado no Proc Natl Acad Sci U S A (2015)

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Por Boucher, Jeremie, Softic, Samir, El Ouaamari, Abdelfattah, Krumpoch, Megan T., Kleinridders, Andre, Kulkarni, Rohit N., O’Neill, Brian T., Kahn, C. Ronald
Publicado no Diabetes (2016)

MyD88 signaling in the CNS is required for development of fatty acid induced leptin resistance and diet-induced obesity

Por Kleinridders, André, Schenten, Dominik, Könner, A. Christine, Belgardt, Bengt F., Mauer, Jan, Okamura, Tomoo, Wunderlich, F. Thomas, Medzhitov, Ruslan, Brüning, Jens C.
Publicado em 2009

Secondary consequences of β-cell inexcitability: Identification and prevention in a murine model of K(ATP)-induced Neonatal Diabetes Mellitus

Por Remedi, Maria Sara, Kurata, Harley T., Scott, Alexis, Wunderlich, F. Thomas, Rother, Eva, Kleinridders, Andre, Tong, Ailing, Brüning, Jens C., Koster, Joseph C., Nichols, Colin G.
Publicado no Cell Metab (2009)

Asc-1, PAT2 and P2RX5 are novel cell surface markers for white, beige and brown adipocytes

Por Ussar, Siegfried, Lee, Kevin Y., Dankel, Simon N., Boucher, Jeremie, Haering, Max-Felix, Kleinridders, Andre, Thomou, Thomas, Xue, Ruidan, Macotela, Yazmin, Cypess, Aaron M., Tseng, Yu-Hua, Mellgren, Gunnar, Kahn, C. Ronald
Publicado no Sci Transl Med (2014)

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Por Gupta, Manoj K., Teo, Adrian Kee Keong, Rao, Tata Nageswara, Bhatt, Shweta, Kleinridders, Andre, Shirakawa, Jun, Takatani, Tomozumi, Hu, Jiang, De Jesus, Dario F., Windmueller, Rebecca, Wagers, Amy J., Kulkarni, Rohit N.
Publicado no Stem Cells Transl Med (2015)

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

Por Cai, Weikang, Sakaguchi, Masaji, Kleinridders, Andre, Gonzalez-Del Pino, Gonzalo, Dreyfuss, Jonathan M., O'Neill, Brian T., Ramirez, Alfred K., Pan, Hui, Winnay, Jonathon N., Boucher, Jeremie, Eck, Michael J., Kahn, C. Ronald
Publicado no Nat Commun (2017)

Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation

Por Jing, Enxuan, O’Neill, Brian T., Rardin, Matthew J., Kleinridders, André, Ilkeyeva, Olga R., Ussar, Siegfried, Bain, James R., Lee, Kevin Y., Verdin, Eric M., Newgard, Christopher B., Gibson, Bradford W., Kahn, C. Ronald
Publicado em 2013

Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance

Por Bailly-Maitre, Béatrice, Belgardt, Bengt F., Jordan, Sabine D., Coornaert, Beatrice, John von Freyend, Miriam, Kleinridders, Andre, Mauer, Jan, Cuddy, Michael, Kress, Christina L., Willmes, Diana, Essig, Manuela, Hampel, Brigitte, Protzer, Ulrike, Reed, John C., Brüning, Jens C.
Publicado em 2010

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

Por O’Neill, Brian T., Lee, Kevin Y., Klaus, Katherine, Softic, Samir, Krumpoch, Megan T., Fentz, Joachim, Stanford, Kristin I., Robinson, Matthew M., Cai, Weikang, Kleinridders, Andre, Pereira, Renata O., Hirshman, Michael F., Abel, E. Dale, Accili, Domenico, Goodyear, Laurie J., Nair, K. Sreekumaran, Kahn, C. Ronald
Publicado no J Clin Invest (2016)