AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

Activation of Agouti-related peptide (AgRP) neurons potently promotes feeding, and chronically altering their activity also affects peripheral glucose homeostasis. We demonstrate that acute activation of AgRP neurons causes insulin resistance through impairment of insulin-stimulated glucose uptake i...

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書誌詳細
出版年:Cell
主要な著者: Steculorum, Sophie M., Ruud, Johan, Karakasilioti, Ismene, Backes, Heiko, Ruud, Linda Engström, Timper, Katharina, Hess, Martin E., Tsaousidou, Eva, Mauer, Jan, Vogt, Merly C., Paeger, Lars, Bremser, Stephan, Klein, Andreas C., Morgan, Donald A., Frommolt, Peter, Brinkkötter, Paul T., Hammerschmidt, Philipp, Benzing, Thomas, Rahmouni, Kamal, Wunderlich, F. Thomas, Kloppenburg, Peter, Brüning, Jens C.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157157/
https://ncbi.nlm.nih.gov/pubmed/27015310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.044
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