Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease

Identification of peptides that activate both tumor-specific helper T (Th) cells and cytotoxic T lymphocytes (CTLs) are important for the induction of effective antitumor immune responses. We focused on a long peptide (LP) derived from lymphocyte antigen 6 complex locus K (LY6K) encompassing both ca...

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Main Authors: Tomita, Yusuke, Yuno, Akira, Tsukamoto, Hirotake, Senju, Satoru, Kuroda, Yasuhiro, Hirayama, Masatoshi, Imamura, Yuya, Yatsuda, Junji, Sayem, Mohammad Abu, Irie, Atsushi, Hamada, Akinobu, Jono, Hirofumi, Yoshida, Koji, Tsunoda, Takuya, Daigo, Yataro, Kohrogi, Hirotsugu, Yoshitake, Yoshihiro, Nakamura, Yusuke, Shinohara, Masanori, Nishimura, Yasuharu
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203508/
https://ncbi.nlm.nih.gov/pubmed/25340007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28100
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