Saturation Diving Alters Folate Status and Biomarkers of DNA Damage and Repair

Por Zwart, Sara R., Jessup, J. Milburn, Ji, Jiuping, Smith, Scott M.
Publicado em 2012

Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

Por Murai, Junko, Zhang, Yiping, Morris, Joel, Ji, Jiuping, Takeda, Shunichi, Doroshow, James H., Pommier, Yves
Publicado em 2014

Implementation of Validated Pharmacodynamic Assays in Multiple Laboratories: Challenges, Successes, and Limitations

Por Kinders, Robert, Ferry-Galow, Kate, Wang, Lihua, Srivastava, Apurva K., Ji, Jiuping (Jay), Parchment, Ralph E.
Publicado em 2014

Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells

Por Ji, Jiuping, Kinders, Robert J., Zhang, Yiping, Rubinstein, Larry, Kummar, Shivaani, Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2011

Differential trapping of PARP1 and PARP2 by clinical PARP inhibitors

Por Murai, Junko, Huang, Shar-yin N., Das, Benu Brata, Renaud, Amelie, Zhang, Yiping, Doroshow, James H., Ji, Jiuping, Takeda, Shunichi, Pommier, Yves
Publicado em 2012

Histone γH2AX and Poly(ADP ribose) as Clinical Pharmacodynamic Biomarkers

Por Redon, Christophe E., Nakamura, Asako J., Zhang, Yongwei, Ji, Jiuping (Jay), Bonner, William M., Kinders, Robert, Parchment, Ralph, Doroshow, James H., Pommier, Yves
Publicado em 2010

Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib

Por Murai, Junko, Huang, Shar-yin N., Renaud, Amèlie, Zhang, Yiping, Ji, Jiuping, Takeda, Shunichi, Morris, Joel, Teicher, Beverly, Doroshow, James H., Pommier, Yves
Publicado em 2013

Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors

Por Do, Khanh, Wilsker, Deborah, Ji, Jiuping, Zlott, Jennifer, Freshwater, Tomoko, Kinders, Robert J., Collins, Jerry, Chen, Alice P., Doroshow, James H., Kummar, Shivaani
Publicado no J Clin Oncol (2015)

Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform

Por Murai, Junko, Marchand, Christophe, Shahane, Sampada A., Sun, Hongmao, Huang, Ruili, Zhang, Yiping, Chergui, Adel, Ji, Jiuping, Doroshow, James H., Jadhav, Ajit, Takeda, Shunichi, Xia, Menghang, Pommier, Yves
Publicado em 2014

Development of a Validated Immunofluorescence Assay for γH2AX as a Pharmacodynamic Marker of Topoisomerase I Inhibitor Activity

Por Kinders, Robert J., Hollingshead, Melinda, Lawrence, Scott, Ji, Jiuping, Tabb, Brian, Bonner, William M., Pommier, Yves, Rubinstein, Larry, Evrard, Yvonne A., Parchment, Ralph E., Tomaszewski, Joseph, Doroshow, James H.
Publicado em 2010

Characterization of Batracylin-Induced Renal and Bladder Toxicity in Rats

Por Davis, Myrtle, Bunin, Deborah I., Samuelsson, Steven J., Altera, Kenneth P., Kinders, Robert J., Lawrence, Scott M, Ji, Jiuping, Ames, Matthew M., Buhrow, Sarah A., Walden, Chad, Reid, Joel M., Rausch, Linda L., Parman, Toufan
Publicado no Toxicol Pathol (2014)

Randomized Phase II trial of Cyclophosphamide and the Oral Poly (ADP-ribose) Polymerase Inhibitor Veliparib in Patients with Recurrent, Advanced Triple-Negative Breast Cancer

Por Kummar, Shivaani, Wade, James L., Oza, Amit M., Sullivan, Daniel, Chen, Alice P., Gandara, David R., Ji, Jiuping, Kinders, Robert J., Wang, Lihua, Allen, Deborah, Coyne, Geraldine O’Sullivan, Steinberg, Seth M., Doroshow, James H.
Publicado no Invest New Drugs (2016)

Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair

Por Villalona-Calero, Miguel A., Duan, Wenrui, Zhao, Weiqiang, Shilo, Konstantin, Schaaf, Larry J., Thurmond, Jennifer, Westman, Judith A., Marshall, John, Xiaobai, Li, Ji, Jiuping, Rose, Jeffrey, Lustberg, Maryam, Bekaii-Saab, Tanios, Chen, Alice, Timmers, Cynthia
Publicado no J Natl Cancer Inst (2016)

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

Por Ji, Jiuping, Zhang, Yiping, Redon, Christophe E., Reinhold, William C., Chen, Alice P., Fogli, Laura K., Holbeck, Susan L., Parchment, Ralph E., Hollingshead, Melinda, Tomaszewski, Joseph E., Dudon, Quentin, Pommier, Yves, Doroshow, James H., Bonner, William M.
Publicado no PLoS One (2017)

DESIGNING PHASE 0 CANCER CLINICAL TRIALS

Por Murgo, Anthony J., Kummar, Shivaani, Rubinstein, Larry, Gutierrez, Martin, Collins, Jerry, Kinders, Robert, Parchment, Ralph E., Ji, Jiuping, Steinberg, Seth M., Yang, Sherry X., Hollingshead, Melinda, Chen, Alice, Helman, Lee, Wiltrout, Robert, Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2008

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues

Por Pfister, Thomas D., Hollingshead, Melinda, Kinders, Robert J., Zhang, Yiping, Evrard, Yvonne A., Ji, Jiuping, Khin, Sonny A., Borgel, Suzanne, Stotler, Howard, Carter, John, Divelbiss, Raymond, Kummar, Shivaani, Pommier, Yves, Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2012

Phase I/Ib Study of Olaparib and Carboplatin in BRCA1 or BRCA2 Mutation-Associated Breast or Ovarian Cancer With Biomarker Analyses

Por Lee, Jung-Min, Hays, John L., Annunziata, Christina M., Noonan, Anne M., Minasian, Lori, Zujewski, Jo Anne, Yu, Minshu, Gordon, Nicolas, Ji, Jiuping, Sissung, Tristan M., Figg, William D., Azad, Nilofer, Wood, Bradford J., Doroshow, James, Kohn, Elise C.
Publicado em 2014

Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

Por Kummar, Shivaani, Kinders, Robert, Gutierrez, Martin E., Rubinstein, Larry, Parchment, Ralph E., Phillips, Lawrence R., Ji, Jiuping, Monks, Anne, Low, Jennifer A., Chen, Alice, Murgo, Anthony J., Collins, Jerry, Steinberg, Seth M., Eliopoulos, Helen, Giranda, Vincent L., Gordon, Gary, Helman, Lee, Wiltrout, Robert, Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2009

Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

Por Kummar, Shivaani, Chen, Alice, Ji, Jiuping, Zhang, Yiping, Reid, Joel M., Ames, Matthew, Jia, Lee, Weil, Marcie, Speranza, Giovanna, Murgo, Anthony J., Kinders, Robert, Wang, Lihua, Parchment, Ralph E., Carter, John, Stotler, Howard, Rubinstein, Larry, Hollingshead, Melinda, Melillo, Giovanni, Pommier, Yves, Bonner, William, Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2011

A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas

Por Kummar, Shivaani, Ji, Jiuping, Morgan, Robert, Lenz, Heinz-Josef, Puhalla, Shannon L., Belani, Chandra P., Gandara, David R., Allen, Deborah, Kiesel, Brian, Beumer, Jan H., Newman, Edward M., Rubinstein, Larry, Chen, Alice, Zhang, Yiping, Wang, Lihua, Kinders, Robert J., Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2012