A Phase 2 Study of Belinostat (PXD101) in Patients with Relapsed or Refractory Acute Myloid Leukemia or Patients Over 60 with Newly-Diagnosed Acute Myloid Leukemia: A California Ca...

Por Kirschbaum, Mark H., Foon, Kenneth A., Frankel, Paul, Ruel, Christopher, Pulone, Bernadette, Tuscano, Joseph M., Newman, Edward M.
Publicado em 2014

A phase I trial of oxaliplatin in combination with docetaxel in patients with advanced solid tumors

Por Iqbal, Syma, Lenz, Heinz-Josef, Gandara, David R., Shibata, Stephen I., Groshen, Susan, Synold, Timothy W., Newman, Edward M.
Publicado em 2013

A Phase II study of VEGF Trap (Aflibercept, NSC 724770) in Patients with MDS: A California Cancer Consortium Study

Por Kirschbaum, Mark, Frankel, Paul, Synold, Timothy W., Zain, Jasmine, Claxton, David, Tuscano, Joseph, Newman, Edward M., Gandara, David R., Lara, Primo N.
Publicado no Br J Haematol (2016)

A Phase I Pharmacodynamic Study of GTI-2040, an Antisense Oligonucleotide Against Ribonuclotide Reductase, in Acute Leukemias: A California Cancer Consortium Study

Por Kirschbaum, Mark H., Frankel, Paul, Synold, Timothy W., Xie, Zhiliang, Yen, Yun, Popplewell, Leslie, Chen, Robert, Aljitawi, Omar S., Tuscano, Joseph M., Chan, Kenneth K., Newman, Edward M.
Publicado no Leuk Lymphoma (2016)

Oral and intravenous pharmacokinetics of 5-fluoro-2’-deoxycytidine and THU in cynomolgus monkeys and humans

Por Holleran, Julianne L., Beumer, Jan H., McCormick, David L., Johnson, William D., Newman, Edward M., Doroshow, James H., Kummar, Shivaani, Covey, Joseph M., Davis, Myrtle, Eiseman, Julie L.
Publicado no Cancer Chemother Pharmacol (2015)

Pharmcodynamics (PD) and Pharmacokinetics (PK) of E7389 (Eribulin, Halichondrin B Analog) During a Phase I Trial in Patients with Advanced Solid Tumors: A California Cancer Consort...

Por Morgan, Robert J., Synold, Timothy W., Longmate, Jeffrey A., Quinn, David I, Gandara, David, Lenz, Heinz-Josef, Ruel, Christopher, Xi, Bixin, Lewis, Michael D., Colevas, A. Dimitrios, Doroshow, James, Newman, Edward M.
Publicado no Cancer Chemother Pharmacol (2015)

A Phase 1 Trial Dose Escalation Study of Tipifarnib on a Week-On, Week-Off Schedule in Relapsed, Refractory or High-Risk Myeloid Leukemia

Por Kirschbaum, Mark, Synold, Timothy, Stein, Anthony S., Tuscano, Joseph, Zain, Jasmine M., Popplewell, Leslie, Karanes, Chatchada, O'Donnell, Margaret R., Pulone, Bernadette, Rincon, Amalia, Wright, John, Frankel, Paul, Forman, Stephen J., Newman, Edward M.
Publicado em 2011

A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fuoro-2′-deoxycytidine, administered with tetrahydrouridine

Por Newman, Edward M., Morgan, Robert J., Kummar, Shivaani, Beumer, Jan H., Blanchard, M. Suzette, Ruel, Christopher, El-Khoueiry, Anthony B., Carroll, Mary I., Hou, Jessie M., Li, Chun, Lenz, Heinz J., Eiseman, Julie L., Doroshow, James H.
Publicado no Cancer Chemother Pharmacol (2015)

Phase I trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study

Por Shibata, Stephen I., Doroshow, James H., Frankel, Paul, Synold, Timothy W., Yen, Yun, Gandara, David R., Lenz, Heinz-Josef, Chow, Warren A., Leong, Lucille A., Lim, Dean, Margolin, Kim A., Morgan, Robert J., Somlo, George, Newman, Edward M.
Publicado em 2009

A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas

Por Kummar, Shivaani, Ji, Jiuping, Morgan, Robert, Lenz, Heinz-Josef, Puhalla, Shannon L., Belani, Chandra P., Gandara, David R., Allen, Deborah, Kiesel, Brian, Beumer, Jan H., Newman, Edward M., Rubinstein, Larry, Chen, Alice, Zhang, Yiping, Wang, Lihua, Kinders, Robert J., Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado em 2012

A phase I and pharmacokinetic study of oral 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced stage solid cancers – A California C...

Por Chao, Joseph, Synold, Timothy W., Morgan, Robert J., Kunos, Charles, Longmate, Jeff, Lenz, Heinz-Josef, Lim, Dean, Shibata, Stephen, Chung, Vincent, Stoller, Ronald G., Belani, Chandra P., Gandara, David R., McNamara, Mark, Gitlitz, Barbara J., Lau, Derick H., Ramalingam, Suresh S., Davies, Angela, Espinoza-Delgado, Igor, Newman, Edward M., Yen, Yun
Publicado em 2011

Phase 1 Study of Pazopanib in Patients with Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

Por Shibata, Stephen I, Chung, Vincent, Synold, Timothy, Longmate, Jeffrey, Suttle, A Benjamin, Ottesen, Lone H, Lenz, Heinz-Josef, Kummar, Shivaani, Harvey, R Donald, Hamilton, Anne, O’Neil, Bert, Sarantopoulos, John, LoRusso, Patricia, Rudek, Michelle A, Dowlati, Afshin, Mulkerin, Daniel, Belani, Chandra P., Gandhi, Leena, Lau, Cecilia, Ivy, S. Percy, Newman, Edward M.
Publicado em 2013