THE NEUROPHARMACOKINETICS OF TEMOZOLOMIDE IN PATIENTS WITH RESECTABLE BRAIN TUMORS: POTENTIAL IMPLICATIONS FOR THE CURRENT APPROACH TO CHEMORADIATION

Por Portnow, Jana, Badie, Behnam, Chen, Mike, Liu, An, Blanchard, Suzette, Synold, Timothy W.
Publicado em 2009

Bioimaging Real-Time PXR-Dependent mdr1a Gene Regulation in mdr1a.fLUC Reporter Mice

Por Gu, Long, Chen, Jasmine, Synold, Timothy W., Forman, Barry M., Kane, Susan E.
Publicado em 2013

Stability and Antibacterial Activity of Cefepime during Continuous Infusion

Por Sprauten, Pål F., Beringer, Paul M., Louie, Stan G., Synold, Timothy W., Gill, Mark A.
Publicado em 2003

A pilot microdialysis study in brain tumor patients to assess changes in intracerebral cytokine levels after craniotomy and in response to treatment with a targeted anti-cancer age...

Por Portnow, Jana, Badie, Behnam, Liu, Xueli, Frankel, Paul, Mi, Shu, Chen, Mike, Synold, Timothy W.
Publicado no J Neurooncol (2014)

A new model for studying tissue-specific mdr1a gene expression in vivo by live imaging

Por Gu, Long, Tsark, Walter M., Brown, Donna A., Blanchard, Suzette, Synold, Timothy W., Kane, Susan E.
Publicado em 2009

Baicalin increases VEGF expression and angiogenesis by activating the ERRα/PGC-1α pathway

Por Zhang, Keqiang, Lu, Jianming, Mori, Taisuke, Smith-Powell, Leslie, Synold, Timothy W., Chen, Shiuan, Wen, Wei
Publicado em 2011

Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase

Por Gao, Qiang, Esworthy, R. Steven, Kim, Byung-Wook, Synold, Timothy W., Smith, David D., Chu, Fong-Fong
Publicado em 2010

A Neuropharmacokinetic Assessment of Bafetinib, a Second Generation Dual BCR-Abl/Lyn Tyrosine Kinase Inhibitor, in Patients with Recurrent High-Grade Gliomas

Por Portnow, Jana, Badie, Behnam, Markel, Susan, Liu, An, D'Apuzzo, Massimo, Frankel, Paul, Jandial, Rahul, Synold, Timothy W.
Publicado em 2013

DNA lesions induced by UV A1 and B radiation in human cells: Comparative analyses in the overall genome and in the p53 tumor suppressor gene

Por Besaratinia, Ahmad, Synold, Timothy W., Chen, Hsiu-Hua, Chang, Cheng, Xi, Bixin, Riggs, Arthur D., Pfeifer, Gerd P.
Publicado em 2005

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing

Por Nikanjam, Mina, Stewart, Clinton F., Takimoto, Chris H., Synold, Timothy W., Beaty, Orren, Fouladi, Maryam, Capparelli, Edmund V.
Publicado no Cancer Chemother Pharmacol (2015)

A phase I trial of oxaliplatin in combination with docetaxel in patients with advanced solid tumors

Por Iqbal, Syma, Lenz, Heinz-Josef, Gandara, David R., Shibata, Stephen I., Groshen, Susan, Synold, Timothy W., Newman, Edward M.
Publicado em 2013

Effects of Iodonium-Class Flavin Dehydrogenase Inhibitors on Growth, Reactive Oxygen Production, Cell Cycle Progression, NADPH Oxidase 1 Levels, and Gene Expression in Human Colon...

Por Doroshow, James H., Gaur, Shikha, Markel, Susan, Lu, Jiamo, van Balgooy, Josephus, Synold, Timothy W., Xi, Bixin, Wu, Xiwei, Juhasz, Agnes
Publicado em 2013

A Phase II study of VEGF Trap (Aflibercept, NSC 724770) in Patients with MDS: A California Cancer Consortium Study

Por Kirschbaum, Mark, Frankel, Paul, Synold, Timothy W., Zain, Jasmine, Claxton, David, Tuscano, Joseph, Newman, Edward M., Gandara, David R., Lara, Primo N.
Publicado no Br J Haematol (2016)

Single-dose pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in mice

Por Synold, Timothy W., Xi, Bixin, Wu, Jun, Yen, Yun, Li, Benjamin C., Yang, Fei, Phillips, John W., Nickols, Nicholas G., Dervan, Peter B.
Publicado em 2012

Phase I Study Evaluating the Combination of Lapatinib (a Her2/Neu and EGFR Inhibitor) and Everolimus (an mTOR Inhibitor) in Patients with Advanced Cancers: South West Oncology Grou...

Por Gadgeel, Shirish M., Lew, Danika L., Synold, Timothy W., LoRusso, Patricia, Chung, Vincent, Christensen, Scott D., Smith, David C., Kingsbury, Laura, Hoering, Antje, Kurzrock, Razelle
Publicado em 2013

A Phase I Pharmacodynamic Study of GTI-2040, an Antisense Oligonucleotide Against Ribonuclotide Reductase, in Acute Leukemias: A California Cancer Consortium Study

Por Kirschbaum, Mark H., Frankel, Paul, Synold, Timothy W., Xie, Zhiliang, Yen, Yun, Popplewell, Leslie, Chen, Robert, Aljitawi, Omar S., Tuscano, Joseph M., Chan, Kenneth K., Newman, Edward M.
Publicado no Leuk Lymphoma (2016)

A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance

Por Zhou, Bingsen, Su, Leila, Hu, Shuya, Hu, Weidong, Yip, M. L. Richard, Wu, Jun, Gaur, Shikha, Smith, D. Lynne, Yuan, Yate-Ching, Synold, Timothy W., Horne, David, Yen, Yun
Publicado em 2013

Pharmcodynamics (PD) and Pharmacokinetics (PK) of E7389 (Eribulin, Halichondrin B Analog) During a Phase I Trial in Patients with Advanced Solid Tumors: A California Cancer Consort...

Por Morgan, Robert J., Synold, Timothy W., Longmate, Jeffrey A., Quinn, David I, Gandara, David, Lenz, Heinz-Josef, Ruel, Christopher, Xi, Bixin, Lewis, Michael D., Colevas, A. Dimitrios, Doroshow, James, Newman, Edward M.
Publicado no Cancer Chemother Pharmacol (2015)

Age-Related Changes in Nanoparticle Albumin-Bound Paclitaxel Pharmacokinetics and Pharmacodynamics: Influence of Chronological Versus Functional Age

Por Hurria, Arti, Blanchard, M. Suzette, Synold, Timothy W., Mortimer, Joanne, Chung, Cathie T., Luu, Thehang, Katheria, Vani, Rotter, Arnold J., Wong, Carol, Choi, Anthony, Feng, Tao, Ramani, Rupal, Doan, Caroline M., Brown, Jaycen, Somlo, George
Publicado no Oncologist (2015)

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma

Por Gutova, Margarita, Goldstein, Leanne, Metz, Marianne, Hovsepyan, Anahit, Tsurkan, Lyudmila G., Tirughana, Revathiswari, Tsaturyan, Lusine, Annala, Alexander J., Synold, Timothy W., Wan, Zesheng, Seeger, Robert, Anderson, Clarke, Moats, Rex A., Potter, Philip M., Aboody, Karen S.
Publicado no Mol Ther Oncolytics (2016)