טוען...
Bioimaging Real-Time PXR-Dependent mdr1a Gene Regulation in mdr1a.fLUC Reporter Mice
The MDR1 gene encodes P-glycoprotein, a transmembrane drug efflux transporter that confers multidrug resistance in cancer cells and affects drug pharmacokinetics by virtue of its expression in the liver, kidney, and colon. Nuclear receptors human steroid and xenobiotic receptor (SXR) and constitutiv...
שמור ב:
Main Authors: | , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657110/ https://ncbi.nlm.nih.gov/pubmed/23532932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.203562 |
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