Modulation of selenium-dependent glutathione peroxidase activity enhances doxorubicin-induced apoptosis, tumour cell killing and hydroxyl radical production in human NCI/ADR-RES ca...

Por Doroshow, James H., Juhasz, Agnes
Publicado no Free Radic Res (2019)

Human Papillomavirus Infection as a Prognostic Factor in Oropharyngeal Squamous Cell Carcinoma Patients Treated in a Prospective Phase II Clinical Trial

Por Jo, Solomon, Juhasz, Agnes, Zhang, Keqiang, Ruel, Christopher, Wilczynski, Sharon P., Yen, Yun, Shibata, Stephen
Publicado em 2009

Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Ca...

Por Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Ge, Yun, Jiang, Guojian, Roy, Krishnendu, Doroshow, James H.
Publicado em 2011

Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues

Por JUHASZ, AGNES, GE, YUN, MARKEL, SUSAN, CHIU, ALICE, MATSUMOTO, LINDA, VAN BALGOOY, JOSEPHUS, ROY, KRISHNENDU, DOROSHOW, JAMES H
Publicado em 2009

Antiproliferative Mechanisms of Action of the Flavin Dehydrogenase Inhibitors Diphenylene Iodonium and Di-2-thienyliodonium Based on Molecular Profiling of the NCI-60 Human Tumor C...

Por Doroshow, James H., Juhasz, Agnes, Ge, Yun, Holbeck, Susan, Lu, Jiamo, Antony, Smitha, Wu, Yongzhong, Jiang, Guojian, Roy, Krishnendu
Publicado em 2012

NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology

Por Meitzler, Jennifer L., Antony, Smitha, Wu, Yongzhong, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Lu, Jiamo, Roy, Krishnendu, Doroshow, James H.
Publicado em 2014

Effects of Iodonium-Class Flavin Dehydrogenase Inhibitors on Growth, Reactive Oxygen Production, Cell Cycle Progression, NADPH Oxidase 1 Levels, and Gene Expression in Human Colon...

Por Doroshow, James H., Gaur, Shikha, Markel, Susan, Lu, Jiamo, van Balgooy, Josephus, Synold, Timothy W., Xi, Bixin, Wu, Xiwei, Juhasz, Agnes
Publicado em 2013

The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph(−) acute lymphoblastic leukemia cells

Por Scuto, Anna, Kirschbaum, Mark, Kowolik, Claudia, Kretzner, Leo, Juhasz, Agnes, Atadja, Peter, Pullarkat, Vinod, Bhatia, Ravi, Forman, Stephen, Yen, Yun, Jove, Richard
Publicado em 2008

Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

Por Liu, Han, Antony, Smitha, Roy, Krishnendu, Juhasz, Agnes, Wu, Yongzhong, Lu, Jiamo, Meitzler, Jennifer L., Jiang, Guojian, Polley, Eric, Doroshow, James H.
Publicado no Oncotarget (2017)

Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

Por WU, YONGHZONG, ANTONY, SMITHA, HEWITT, STEPHEN M., JIANG, GUOJIAN, YANG, SHERRY X., MEITZLER, JENNIFER L., JUHASZ, AGNES, LU, JIAMO, LIU, HAN, DOROSHOW, JAMES H., ROY, KRISHNENDU
Publicado em 2013

Activation of Toll-Like Receptor 4 Is Required for the Synergistic Induction of Dual Oxidase 2 and Dual Oxidase A2 by Interferon-γ and Lipopolysaccharide in Human Pancreatic Cancer...

Por Wu, Yongzhong, Lu, Jiamo, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Meitzler, Jennifer L., Hollingshead, Melinda, Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.
Publicado em 2013

Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

Por Antony, Smitha, Wu, Yongzhong, Hewitt, Stephen M., Anver, Miriam R., Butcher, Donna, Jiang, Guojian, Meitzler, Jennifer L., Liu, Han, Juhasz, Agnes, Lu, Jiamo, Roy, Krishnendu K., Doroshow, James H.
Publicado em 2013

Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H(2)O(2)-induced, ERK-associated up-regulation of HIF-1α and VEGF-A

Por Wu, Yongzhong, Meitzler, Jennifer L., Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Jiang, Guojian, Liu, Han, Hollingshead, Melinda, Haines, Diana C., Butcher, Donna, Panter, Michaela S., Roy, Krishnendu, Doroshow, James H.
Publicado no Oncotarget (2016)

NADPH oxidase 1 is highly expressed in human large and small bowel cancers

Por Lu, Jiamo, Jiang, Guojian, Wu, Yongzhong, Antony, Smitha, Meitzler, Jennifer L., Juhasz, Agnes, Liu, Han, Roy, Krishnendu, Makhlouf, Hala, Chuaqui, Rodrigo, Butcher, Donna, Konaté, Mariam M., Doroshow, James H.
Publicado no PLoS One (2020)

IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells

Por Wu, Yongzhong, Konaté, Mariam M., Lu, Jiamo, Makhlouf, Hala, Chuaqui, Rodrigo, Antony, Smitha, Meitzler, Jennifer L., Difilippantonio, Michael J., Liu, Han, Juhasz, Agnes, Jiang, Guojian, Dahan, Iris, Roy, Krishnendu, Doroshow, James H.
Publicado no J Immunol (2019)

NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction

Por Juhasz, Agnes, Markel, Susan, Gaur, Shikha, Liu, Han, Lu, Jiamo, Jiang, Guojian, Wu, Xiwei, Antony, Smitha, Wu, Yongzhong, Melillo, Giovanni, Meitzler, Jennifer L., Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.
Publicado no J Biol Chem (2017)

Decoding NADPH oxidase 4 expression in human tumors

Por Meitzler, Jennifer L., Makhlouf, Hala R., Antony, Smitha, Wu, Yongzhong, Butcher, Donna, Jiang, Guojian, Juhasz, Agnes, Lu, Jiamo, Dahan, Iris, Jansen-Dürr, Pidder, Pircher, Haymo, Shah, Ajay M., Roy, Krishnendu, Doroshow, James H.
Publicado no Redox Biol (2017)

Quantification of chemotherapeutic target gene mRNA expression in human breast cancer biopsies: Comparison of real‐time reverse transcription‐PCR vs. Relative quantification revers...

Por Juhasz, Agnes, Frankel, Paul, Cheng, Catherine, Rivera, Hector, Vishwanath, Reena, Chiu, Alice, Margolin, Kim, Yen, Yun, Newman, Edward M., Synold, Tim, Wilczynski, Sharon, Lenz, Heinz‐Josef, Gandara, David, Albain, Kathy S., Longmate, Jeffrey, Doroshow, James H.
Publicado no J Clin Lab Anal (2003)

Characterization of Potent and Selective Iodonium-Class Inhibitors of NADPH Oxidases

Por Lu, Jiamo, Risbood, Prabhakar, Kane, Charles T., Hossain, Md Tafazzal, Anderson, Larry, Hill, Kimberly, Monks, Anne, Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Harris, Erik, Roy, Krishnendu, Meitzler, Jennifer L., Konaté, Mariam, Doroshow, James H.
Publicado no Biochem Pharmacol (2017)

NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27(Kip1) expression in malignant melanoma and other human tumors

Por Antony, Smitha, Jiang, Guojian, Wu, Yongzhong, Meitzler, Jennifer L., Makhlouf, Hala R., Haines, Diana C., Butcher, Donna, Hoon, Dave S., Ji, Jiuping, Zhang, Yiping, Juhasz, Agnes, Lu, Jiamo, Liu, Han, Dahan, Iris, Konate, Mariam, Roy, Krishnendu K., Doroshow, James H.
Publicado no Mol Carcinog (2017)