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Activation of Toll-Like Receptor 4 Is Required for the Synergistic Induction of Dual Oxidase 2 and Dual Oxidase A2 by Interferon-γ and Lipopolysaccharide in Human Pancreatic Cancer Cell Lines(§)

Pancreatitis is associated with release of pro-inflammatory cytokines and reactive oxygen species and plays an important role in the development of pancreatic cancer. We recently demonstrated that dual oxidase 2 (Duox2), an NADPH oxidase essential for ROS-related, gastrointestinal host defense, is r...

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Bibliographic Details
Main Authors: Wu, Yongzhong, Lu, Jiamo, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Meitzler, Jennifer L., Hollingshead, Melinda, Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563939/
https://ncbi.nlm.nih.gov/pubmed/23296709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201725
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