NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction

Reactive oxygen species (ROS) play a critical role in cell signaling and proliferation. NADPH oxidase 1 (NOX1), a membrane-bound flavin dehydrogenase that generates O(2)(˙̄), is highly expressed in colon cancer. To investigate the role that NOX1 plays in colon cancer growth, we used shRNA to decreas...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Juhasz, Agnes, Markel, Susan, Gaur, Shikha, Liu, Han, Lu, Jiamo, Jiang, Guojian, Wu, Xiwei, Antony, Smitha, Wu, Yongzhong, Melillo, Giovanni, Meitzler, Jennifer L., Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427267/
https://ncbi.nlm.nih.gov/pubmed/28330872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.768283
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