NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27(Kip1) expression in malignant melanoma and other human tumors

NADPH oxidase 5 (NOX5) generated reactive oxygen species (ROS) have been implicated in signaling cascades that regulate cancer cell proliferation. To evaluate and validate NOX5 expression in human tumors, we screened a broad range of tissue microarrays (TMAs), and report substantial overexpression o...

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Publicado no:Mol Carcinog
Main Authors: Antony, Smitha, Jiang, Guojian, Wu, Yongzhong, Meitzler, Jennifer L., Makhlouf, Hala R., Haines, Diana C., Butcher, Donna, Hoon, Dave S., Ji, Jiuping, Zhang, Yiping, Juhasz, Agnes, Lu, Jiamo, Liu, Han, Dahan, Iris, Konate, Mariam, Roy, Krishnendu K., Doroshow, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675809/
https://ncbi.nlm.nih.gov/pubmed/28762556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22708
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