Characterization of Potent and Selective Iodonium-Class Inhibitors of NADPH Oxidases

The NADPH oxidases (NOXs) play a recognized role in the development and progression of inflammation-associated disorders, as well as cancer. To date, several NOX inhibitors have been developed, through either high throughput screening or targeted disruption of NOX interaction partners, although only...

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Veröffentlicht in:Biochem Pharmacol
Hauptverfasser: Lu, Jiamo, Risbood, Prabhakar, Kane, Charles T., Hossain, Md Tafazzal, Anderson, Larry, Hill, Kimberly, Monks, Anne, Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Harris, Erik, Roy, Krishnendu, Meitzler, Jennifer L., Konaté, Mariam, Doroshow, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610936/
https://ncbi.nlm.nih.gov/pubmed/28709950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.07.007
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