Characterization of Potent and Selective Iodonium-Class Inhibitors of NADPH Oxidases

The NADPH oxidases (NOXs) play a recognized role in the development and progression of inflammation-associated disorders, as well as cancer. To date, several NOX inhibitors have been developed, through either high throughput screening or targeted disruption of NOX interaction partners, although only...

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Foilsithe in:Biochem Pharmacol
Main Authors: Lu, Jiamo, Risbood, Prabhakar, Kane, Charles T., Hossain, Md Tafazzal, Anderson, Larry, Hill, Kimberly, Monks, Anne, Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Liu, Han, Jiang, Guojian, Harris, Erik, Roy, Krishnendu, Meitzler, Jennifer L., Konaté, Mariam, Doroshow, James H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610936/
https://ncbi.nlm.nih.gov/pubmed/28709950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.07.007
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