Llwytho...
Single-dose pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in mice
PURPOSE: Pyrrole–imidazole (Py-Im) polyamides are programmable, sequence-specific DNA minor groove–binding ligands. Previous work in cell culture has shown that various polyamides can be used to modulate the transcriptional programs of oncogenic transcription factors. In this study, two hairpin poly...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Springer-Verlag
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3456924/ https://ncbi.nlm.nih.gov/pubmed/22907527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1954-3 |
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