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Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide
Pyrrole-imidazole (Py–Im) polyamides are synthetic non-genotoxic minor groove-binding small molecules. We hypothesized that Py–Im polyamides can modulate the cellular response to ionizing radiation. Pre-treatment of cells with a Py-Im polyamide prior to exposure to ionizing radiation resulted in a d...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929528/ https://ncbi.nlm.nih.gov/pubmed/29715291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196803 |
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