Age-Related Changes in Nanoparticle Albumin-Bound Paclitaxel Pharmacokinetics and Pharmacodynamics: Influence of Chronological Versus Functional Age

PURPOSE. This study evaluated age-related changes in pharmacokinetic and pharmacodynamic parameters of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) in patients with metastatic breast cancer. METHODS. Forty patients received nab-paclitaxel (100 mg/m(2) weekly for 3 weeks followed by a 1-wee...

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Bibliografiske detaljer
Udgivet i:Oncologist
Main Authors: Hurria, Arti, Blanchard, M. Suzette, Synold, Timothy W., Mortimer, Joanne, Chung, Cathie T., Luu, Thehang, Katheria, Vani, Rotter, Arnold J., Wong, Carol, Choi, Anthony, Feng, Tao, Ramani, Rupal, Doan, Caroline M., Brown, Jaycen, Somlo, George
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2015
Fag:
Geriatric Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294604/
https://ncbi.nlm.nih.gov/pubmed/25492923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0202
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