Age-Related Changes in Nanoparticle Albumin-Bound Paclitaxel Pharmacokinetics and Pharmacodynamics: Influence of Chronological Versus Functional Age

PURPOSE. This study evaluated age-related changes in pharmacokinetic and pharmacodynamic parameters of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) in patients with metastatic breast cancer. METHODS. Forty patients received nab-paclitaxel (100 mg/m(2) weekly for 3 weeks followed by a 1-wee...

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Detaylı Bibliyografya
Yayımlandı:Oncologist
Asıl Yazarlar: Hurria, Arti, Blanchard, M. Suzette, Synold, Timothy W., Mortimer, Joanne, Chung, Cathie T., Luu, Thehang, Katheria, Vani, Rotter, Arnold J., Wong, Carol, Choi, Anthony, Feng, Tao, Ramani, Rupal, Doan, Caroline M., Brown, Jaycen, Somlo, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AlphaMed Press 2015
Konular:
Geriatric Oncology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294604/
https://ncbi.nlm.nih.gov/pubmed/25492923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0202
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