Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines

od Parise, Robert A., Anyang, Bean N., Eiseman, Julie L., Egorin, Merrill J., Covey, Joseph M., Beumer, Jan H.
Wydane 2012

Comparative Metabolism of Batracylin (NSC 320846) and N-acetylbatracylin (NSC 611001) Using Human, Dog, and Rat Preparations In Vitro

od Covey, Joseph M, Reid, Joel M, Buhrow, Sarah A, Kuffel, Mary, Walden, Chad, Behrsing, Holger, Ames, Matthew M
Wydane w J Drug Metab Toxicol (2016)

Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776

od Holleran, Julianne L., Parise, Robert A., Yellow-Duke, Archibong E., Egorin, Merrill J., Eiseman, Julie L., Covey, Joseph M., Beumer, Jan H.
Wydane 2010

LC–MS/MS quantification of a neuropeptide fragment kisspeptin-10 (NSC 741805) and characterization of its decomposition product and pharmacokinetics in rats

od Liu, Zhongfa, Ren, Chen, Jones, William, Chen, Ping, Seminara, Stephanie B., Chan, Yee-Ming, Smith, Nicola F., Covey, Joseph M., Wang, Jeffrey, Chan, Kenneth K.
Wydane 2013

Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma

od Parise, Robert A., Beumer, Jan H., Kangani, Cyrous O., Holleran, Julianne L., Eiseman, Julie L., Smith, Nicola F., Covey, Joseph M., Perrine, Susan P., Egorin, Merrill J.
Wydane 2007

Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice

od Beumer, Jan H., Eiseman, Julie L., Parise, Robert A., Florian, Jeffry A., Joseph, Erin, D’Argenio, David Z., Parker, Robert S., Kay, Brittany, Covey, Joseph M., Egorin, Merrill J.
Wydane 2007

Oral and intravenous pharmacokinetics of 5-fluoro-2’-deoxycytidine and THU in cynomolgus monkeys and humans

od Holleran, Julianne L., Beumer, Jan H., McCormick, David L., Johnson, William D., Newman, Edward M., Doroshow, James H., Kummar, Shivaani, Covey, Joseph M., Davis, Myrtle, Eiseman, Julie L.
Wydane w Cancer Chemother Pharmacol (2015)

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

od Srivastava, Apurva K., Hollingshead, Melinda G., Govindharajulu, Jeevan P., Covey, Joseph M., Liston, Dane, Simpson, Melanie A., Peggins, James O., Bottaro, Donald P., Wright, John J., Kinders, Robert J., Doroshow, James H., Parchment, Ralph E.
Wydane w Mol Cancer Ther (2018)

Plasma pharmacokinetics of the indenoisoquinoline topoisomerase I inhibitor, NSC 743400, in rats and dogs

od Muzzio, Miguel, Hu, Shu-Chieh, Holleran, Julianne L., Parise, Robert A., Eiseman, Julie L., Yellow-Duke, Archibong E., Covey, Joseph M., Glaze, Elizabeth R., Engelke, Kory, Egorin, Merrill J., McCormicka, David L., Beumer, Jan H.
Wydane w Cancer Chemother Pharmacol (2015)

Preclinical Pharmacokinetics Study of R- and S-Enantiomers of the Histone Deacetylase Inhibitor, AR-42 (NSC 731438), in Rodents

od Cheng, Hao, Xie, Zhiliang, Jones, William P., Wei, Xiaohui Tracey, Liu, Zhongfa, Wang, Dasheng, Kulp, Samuel K., Wang, Jiang, Coss, Christopher C., Chen, Ching-Shih, Marcucci, Guido, Garzon, Ramiro, Covey, Joseph M., Phelps, Mitch A., Chan, Kenneth K.
Wydane w AAPS J (2016)

Characterization of Silvestrol Pharmacokinetics in Mice Using Liquid Chromatography–Tandem Mass Spectrometry

od Saradhi, U. V. R. Vijaya, Gupta, Sneha V., Chiu, Ming, Wang, Jiang, Ling, Yonghua, Liu, Zhongfa, Newman, David J., Covey, Joseph M., Kinghorn, A. Douglas, Marcucci, Guido, Lucas, David M., Grever, Michael R., Phelps, Mitch A., Chan, Kenneth K.
Wydane 2011

Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice

od Beumer, Jan H., Eiseman, Julie L., Gilbert, Judith A., Holleran, Julianne L., Yellow-Duke, Archibong E., Clausen, Dana M., D’Argenio, David Z., Ames, Matthew M., Hershberger, Pamela A., Parise, Robert A., Bai, Lihua, Covey, Joseph M., Egorin, Merrill J.
Wydane 2010

Intravenous 5-fluoro-2′-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors...

od Coyne, Geraldine O.’Sullivan, Wang, Lihua, Zlott, Jennifer, Juwara, Lamin, Covey, Joseph M., Beumer, Jan H., Cristea, Mihaela C., Newman, Edward M., Koehler, Stephen, Nieva, Jorge J., Garcia, Agustin A., Gandara, David R., Miller, Brandon, Khin, Sonny, Miller, Sarah B., Steinberg, Seth M., Rubinstein, Larry, Parchment, Ralph E., Kinders, Robert J., Piekarz, Richard L., Kummar, Shivaani, Chen, Alice P., Doroshow, James H.
Wydane w Cancer Chemother Pharmacol (2020)

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors

od Takebe, Naoko, Coyne, Geraldine O'Sullivan, Kummar, Shivaani, Collins, Jerry, Reid, Joel M., Piekarz, Richard, Moore, Nancy, Juwara, Lamin, Johnson, Barry C., Bishop, Rachel, Lin, Frank I., Mena, Esther, Choyke, Peter L., Lindenberg, M. Liza, Rubinstein, Larry V., Bonilla, Cecilia Monge, Goetz, Matthew P., Ames, Matthew M., McGovern, Renee M., Streicher, Howard, Covey, Joseph M., Doroshow, James H., Chen, Alice P.
Wydane w Oncotarget (2021)

NCI Comparative Oncology Program Testing of Indenoisoquinoline Topoisomerase I Inhibitors in Naturally Occurring Canine Lymphoma

od Burton, Jenna H., Mazcko, Christina, Leblanc, Amy, Covey, Joseph M., Ji, Jiuping, Kinders, Robert J., Parchment, Ralph E., Khanna, Chand, Paoloni, Melissa, Lana, Sue, Weishaar, Kristen, London, Cheryl, Kisseberth, William, Krick, Erika, Vail, David, Childress, Michael, Bryan, Jeffrey, Baber, Lisa, Ehrhart, E.J., Kent, Michael, Fan, Timothy, Kow, Kelvin, Northup, Nicole, Wilson-Robles, Heather, Tomaszewski, Joseph, Holleran, Julianne L., Muzzio, Miguel, Eiseman, Julie, Beumer, Jan H., Doroshow, James H., Pommier, Yves
Wydane w Clin Cancer Res (2018)